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Home » Topics » Drugs » Vaccine

Vaccine
Vaccine RSS Feed RSS

CDC’s ACIP meeting rescheduled

March 24, 2025
By Karen Carey
A meeting of the CDC’s Advisory Committee on Immunization Practices (ACIP) was rescheduled for April 15-16, according to the Federal Register.
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mRNA on digital background
Immuno-oncology

Everest Medicines’ mRNA cancer vaccine EVM-14 gains IND clearance

March 24, 2025
Everest Medicines Ltd. has obtained IND clearance from the FDA for EVM-14, an off-the-shelf mRNA cancer vaccine targeting multiple tumor-associated antigens and designed to treat various cancers, including non-small-cell lung cancer and head and neck cancer.
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Vaccine vial and syringe

Aim seeks approval of first serum-free human rabies vaccine

March 18, 2025
By Marian (YoonJee) Chu
Aim Vaccine Co. Ltd. may become the first company to gain regulatory clearance of a prophylactic iterative serum-free human rabies vaccine. Beijing-based Aim said it is preparing a regulatory submission of its independently developed rabies vaccine based on positive phase III results that showed good safety, immunogenicity and immune persistence.
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Look, Ma, no adcom

March 17, 2025
By Mari Serebrov
Breaking with a 30-year tradition, the U.S. FDA selected the strains for the next flu vaccine March 13 without convening its independent vaccine advisory committee. Instead, the agency brought together 15 scientific and public health experts from within the FDA, the CDC and the Department of Defense to make the recommendations for the next flu season. That group met the same day that the agency’s Vaccines and Related Biological Products Advisory Committee had been scheduled to make the selection.
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CDC headquarters

US CDC nomination withdrawn, reforms in the works

March 13, 2025
By Mari Serebrov
Shortly before the Senate Health, Education, Labor and Pensions Committee was to hold the first ever confirmation hearing for a U.S. CDC director March 13, it issued a statement saying the hearing was canceled due to the White House withdrawing its nomination of Dave Weldon, a physician and former congressman from Florida.
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Vaccine vial and syringe

Aim seeks approval of first serum-free human rabies vaccine

March 12, 2025
By Marian (YoonJee) Chu
Aim Vaccine Co. Ltd. may become the first company to gain regulatory clearance of a prophylactic iterative serum-free human rabies vaccine. Beijing-based Aim said it is preparing a regulatory submission of its independently developed rabies vaccine based on positive phase III results that showed good safety, immunogenicity and immune persistence.
Read More
Gloved hand holding vial, syringe
Infection

Using computational biology to develop pan-H5 vaccine against avian influenza

March 11, 2025
Researchers from Diosynvax Ltd. presented data from a study that aimed to evaluate the efficacy of a pan-H5 vaccine designed using computational biology and being developed for protection against avian influenza.
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Vial and syringe with molecule structure
Immuno-oncology

Preclinical and early clinical safety assessment of a new synthetic peptide-peptide cancer vaccine

March 6, 2025
Peptide-based vaccines deliver tumor-specific antigens to dendritic cells (DCs), triggering tumor-targeted T-cell responses. A peptide-peptide conjugate technology previously developed by researchers from Uppsala University and collaborators enhances this process by using multiple tetanus toxin-derived B-cell epitopes (MTTEs) to facilitate in vivo antigen delivery and DC activation.
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Jay Bhattacharya, nominee for U.S. NIH director

Bhattacharya shares his vision for US NIH

March 5, 2025
By Mari Serebrov
Jay Bhattacharya will have his work cut out for him if he wins confirmation as the next director of the U.S. NIH. Besides getting NIH committees back on track to evaluate grant applications and calming the fears of researchers and other staff who have seen about 1,200 colleagues cut from their ranks in recent weeks, Bhattacharya will face the task of rebuilding public trust in the NIH itself.
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Infant receiving vaccine

Vaxcyte phase II PCV valve to open shortly, Pfizer sizers alert

March 3, 2025
By Randy Osborne
As U.S. regulatory uncertainty swirls around the vaccine space and health care in general, Vaxcyte Inc. stands poised for a readout of phase II infant data by the end of this quarter with VAX-24, the 24-valent pneumococcal conjugate vaccine (PCV). The San Carlos, Calif.-based firm will offer top-line safety, tolerability, and immunogenicity data, to be followed by top-line data with the booster dose by the end of this year.
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