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Home » Topics » Drugs » Vaccine

Vaccine
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Mycobacterium tuberculosis
Infection

L3T mRNA vaccine platform shows preclinical prophylactic and therapeutic activity against TB

April 8, 2025
New vaccines to control tuberculosis (TB) are urgently needed to fight the global burden of the disease, the increase of resistant strains and the lack of effective vaccines to prevent latent TB infections.
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Red dollar sign under microscope

Trump cuts are 'gutting' research grants, 'destabilizing' science

April 4, 2025
By Nuala Moran
“The nation’s scientific enterprise is being decimated.” That statement in an open letter “to the American people” signed by 1,800 members of the U.S. National Academies, is made concrete in a list of 709 NIH grants – and counting – that have been axed since President Donald Trump was inaugurated on Jan. 20.
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Woman receiving vaccine

Flamingo cancer vaccine in phase III pink, Greenwich time nigh?

April 2, 2025
By Randy Osborne
Greenwich Lifesciences Inc. followed a February update with another on the phase III Flamingo-01 trial, providing open-label immune response data for GLSI-100, a HER2/neu peptide vaccine immunotherapy to prevent breast cancer recurrences in patients who have completed standard therapy. Specifically, GLSI-100 combines GP2, the HER2/neu-derived peptide, with granulocyte-macrophage colony-stimulating factor.
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Red dollar sign under microscope

Trump cuts are 'gutting' research grants, 'destabilizing' science

April 2, 2025
By Nuala Moran
“The nation’s scientific enterprise is being decimated.” That statement in an open letter “to the American people” signed by 1,800 members of the U.S. National Academies, is made concrete in a list of 709 NIH grants – and counting – that have been axed since President Donald Trump was inaugurated on Jan. 20. A grant tracker, based on information published by the Department of Health and Human Sciences, and self-reported terminations from scientists, includes 88 vaccine-related projects, 45 cancer research grants and 231 awards made for HIV research.
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Vaccine vials and syringe in a martini glass.
Cardiovascular

A nanoparticle-based 'cocktail' vaccine against atherosclerosis

April 2, 2025
In a study published in Nature Communications, researchers from Nanjing University present a novel nanovaccine cocktail formulated by individual conjugation of antigen p210 and adjuvant CpG ODNs onto superparamagnetic iron oxide nanoparticles (SPIONs).
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Global vaccine.png
Immune

Institut Pasteur advances Lassa fever vaccine based on new MOPEVAC platform

April 1, 2025
An Institut Pasteur team has developed an original vaccine platform known as MOPEVAC, that will strengthen the organization’s pandemic preparedness initiatives, with the platform’s first vaccine candidate, which targets Lassa fever, set to enter the clinic.
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Vaccine vials and syringe

Vaxcyte sights set on next results after ‘big moment’ with PCV

March 31, 2025
By Randy Osborne
Vaxcyte Inc. characterized its latest phase II data with VAX-24 as positive but Wall Street wasn’t so sure about the dose-finding outcomes with the 24-valent pneumococcal conjugate vaccine (PCV), and shares of the San Carlos, Calif.-based firm (NASDAQ:PCVX) closed March 31 at $37.76, down $31.70, or 46%.
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Marks’ departure intensifies regulatory uncertainty at US FDA

March 31, 2025
By Mari Serebrov
Peter Marks’ March 28 letter giving one week’s notice of his resignation as director of the U.S. FDA’s Center for Biologics Evaluation and Research (CBER) is sending more ripples of uncertainty throughout the industry. Marks, who has helmed CBER for nearly a decade, blamed his departure on recently confirmed Health and Human Services (HHS) Secretary Robert Kennedy, who has made a career out of his anti-vaccine stance.
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CDC’s ACIP meeting rescheduled

March 24, 2025
By Karen Carey
A meeting of the CDC’s Advisory Committee on Immunization Practices (ACIP) was rescheduled for April 15-16, according to the Federal Register.
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mRNA on digital background
Immuno-oncology

Everest Medicines’ mRNA cancer vaccine EVM-14 gains IND clearance

March 24, 2025
Everest Medicines Ltd. has obtained IND clearance from the FDA for EVM-14, an off-the-shelf mRNA cancer vaccine targeting multiple tumor-associated antigens and designed to treat various cancers, including non-small-cell lung cancer and head and neck cancer.
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