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Home » Topics » Drugs » Vaccine

Vaccine
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CDC headquarters

US CDC nomination withdrawn, reforms in the works

March 13, 2025
By Mari Serebrov
Shortly before the Senate Health, Education, Labor and Pensions Committee was to hold the first ever confirmation hearing for a U.S. CDC director March 13, it issued a statement saying the hearing was canceled due to the White House withdrawing its nomination of Dave Weldon, a physician and former congressman from Florida.
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Vaccine vial and syringe

Aim seeks approval of first serum-free human rabies vaccine

March 12, 2025
By Marian (YoonJee) Chu
Aim Vaccine Co. Ltd. may become the first company to gain regulatory clearance of a prophylactic iterative serum-free human rabies vaccine. Beijing-based Aim said it is preparing a regulatory submission of its independently developed rabies vaccine based on positive phase III results that showed good safety, immunogenicity and immune persistence.
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Gloved hand holding vial, syringe
Infection

Using computational biology to develop pan-H5 vaccine against avian influenza

March 11, 2025
Researchers from Diosynvax Ltd. presented data from a study that aimed to evaluate the efficacy of a pan-H5 vaccine designed using computational biology and being developed for protection against avian influenza.
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Vial and syringe with molecule structure
Immuno-oncology

Preclinical and early clinical safety assessment of a new synthetic peptide-peptide cancer vaccine

March 6, 2025
Peptide-based vaccines deliver tumor-specific antigens to dendritic cells (DCs), triggering tumor-targeted T-cell responses. A peptide-peptide conjugate technology previously developed by researchers from Uppsala University and collaborators enhances this process by using multiple tetanus toxin-derived B-cell epitopes (MTTEs) to facilitate in vivo antigen delivery and DC activation.
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Jay Bhattacharya, nominee for U.S. NIH director

Bhattacharya shares his vision for US NIH

March 5, 2025
By Mari Serebrov
Jay Bhattacharya will have his work cut out for him if he wins confirmation as the next director of the U.S. NIH. Besides getting NIH committees back on track to evaluate grant applications and calming the fears of researchers and other staff who have seen about 1,200 colleagues cut from their ranks in recent weeks, Bhattacharya will face the task of rebuilding public trust in the NIH itself.
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Infant receiving vaccine

Vaxcyte phase II PCV valve to open shortly, Pfizer sizers alert

March 3, 2025
By Randy Osborne
As U.S. regulatory uncertainty swirls around the vaccine space and health care in general, Vaxcyte Inc. stands poised for a readout of phase II infant data by the end of this quarter with VAX-24, the 24-valent pneumococcal conjugate vaccine (PCV). The San Carlos, Calif.-based firm will offer top-line safety, tolerability, and immunogenicity data, to be followed by top-line data with the booster dose by the end of this year.
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Colorized scanning electron micrograph of E. coli bacteria.
Immune

CARB-X funds Immunethep’s conjugated peptide-based vaccine for E. coli infections

Feb. 26, 2025
CARB-X (Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator) has announced it will award US$2 million to Immunethep SA to develop a conjugated peptide-based vaccine to prevent infections from all invasive serotypes of Escherichia coli.
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Art concept for vaccine for cancer
Immuno-oncology

IO-112 modulates tumor macrophages, allows control of tumor microenvironment

Feb. 20, 2025
Io Biotech Aps has presented preclinical data regarding their Arg1-derived peptide cancer vaccine IO-112 as a potential immunotherapeutic that would allow controlling the tumor microenvironment.
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New chikungunya vaccine from Bavarian Nordic wins FDA nod

Feb. 18, 2025
By Lee Landenberger
With the U.S. FDA’s approval of Vimkunya, Bavarian Nordic A/S is now in the chikungunya virus infection mix along with Valneva SE’s Ixchiq. A single-dose, adjuvanted virus-like particle-based vaccine to protect against the chikungunya virus infection, Vimkunya is the first of its kind available in the U.S. for those age 12 and older.
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GSK’s meningitis vaccine second pentavalent approved by the FDA

Feb. 18, 2025
By Lee Landenberger
A second pentavalent vaccine for preventing meningococcal disease has been approved by the U.S. FDA. GSL plc’s Penmenvy will now go up against Pfizer Inc.’s Penbraya, which had a two-year head start in the market.
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