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BioWorld - Thursday, February 19, 2026
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Brain and DNA

Epilepsygtx's $33M advances focal epilepsy gene therapy

Dec. 10, 2025
By Nuala Moran
No Comments
Epilepsygtx Ltd. has raised a $33 million series A to fund a phase I/IIa trial of EPY-201, a gene therapy for treating drug-resistant focal epilepsy.
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Pill with British pound sign

UK cuts new drug rebate to 14.5% for 2026, down from 22.5%

Dec. 10, 2025
By Nuala Moran
No Comments
The U.K. government has announced it will cut the rebate pharma companies have to pay on net sales of new drugs, reducing the rate from the record of 22.5% in 2025 to 14.5% for 2026. That is less than the 15% cap agreed earlier this month as part of a U.K./U.S. economic prosperity deal, which placed a requirement on the U.K. to improve the operating environment for pharmaceutical companies.
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Pen and ripped contract

Alcon sweetens offer for Staar, major shareholders still unimpressed

Dec. 10, 2025
By Holland Johnson
Alcon AG reported on Dec. 9 that it had sweetened its offer for intraocular lens maker Staar Surgical Co., raising its offer by roughly 10% to $30.75 a share from its prior bid of $28 a share. The revised offer comes on the heels of the expiration of Staar’s go-shop period on Dec. 8, in which Lake Forest, Calif.-based Staar said no superior offers were received.
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Roche building

Roche secures CE mark for vaginitis diagnostic test

Dec. 10, 2025
By Shani Alexander
Roche AG received CE mark for its cobas Bacterial Vaginosis/Candida Vaginitis assay, which will help to improve accuracy in detecting vaginitis in women. The molecular test identifies specific bacteria and yeast responsible for BV and CV from vaginal samples collected using the cobas PCR Media proprietary tube.
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Colorized transmission electron micrograph of an mpox virus particle
Infection

New recombinant strain of mpox virus identified in the UK

Dec. 10, 2025
By Nuala Moran
No Comments
The UK Health Security Agency (UKHSA) has identified a new recombinant strain of mpox (formerly monkeypox) that contains elements of clade Ib and clade IIb of the virus, in a traveler who recently returned from Asia. In a paper describing the new strain, the researchers at UKHSA say it is not possible to determine from a single genome how long the recombinant virus has been in circulation, or whether it will have a fitness benefit over currently circulating lineages.
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Novartis, Relation join a $1.7B collaboration for atopic disease

Dec. 9, 2025
No Comments
Relation Therapeutics Ltd. will collaborate with Novartis AG in a $1.7 billion deal to develop multiple programs to find and advance targets for treating atopic diseases caused by immune dysregulation. Novartis will pay Relation an up-front amount, an equity investment and R&D funding of $55 million. It’s the company’s second deal with big pharma in the past 12 months.
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Colorized transmission electron micrograph of an mpox virus particle

New recombinant strain of mpox virus identified in the UK

Dec. 9, 2025
By Nuala Moran
No Comments
The UK Health Security Agency has identified a new recombinant strain of mpox (formerly monkeypox) that contains elements of clade Ib and clade IIb of the virus, in a traveler who recently returned from Asia.
Read More
Businessman signing documents

Teleflex selling 3 business units for $2.03B

Dec. 9, 2025
By Holland Johnson
Teleflex Inc. reported plans to sell its Acute Care, Interventional Urology and OEM businesses to two buyers for $2.03 billion. Intersurgical Ltd. will acquire the Acute Care and Interventional Urology units for $530 million. Additionally, private equity firms Montagu and Kohlberg are buying its OEM contract manufacturing business for $1.5 billion.
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Human heart within crosshairs

Levron emerges with cardio-respiratory physiology assist tech

Dec. 9, 2025
By Shani Alexander
Levron Medical Ltd. recently exited stealth mode to advance its cardio-respiratory physiology assist technology, designed to treat heart failure by synchronizing the heart and lungs. The approach harnesses the natural ‘respiratory pump’ to assist cardiac function and create what the company claims to be a new category of heart failure treatment.
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Ireland plots to safeguard US investment in biomanufacturing sector

Dec. 8, 2025
By Nuala Moran
No Comments
Ireland is taking stock of the implications Trump administration tariffs and drug pricing policies hold for its world-leading biomanufacturing sector, which has been largely built on the back of investment by U.S. pharma companies – and is hugely reliant on exports to the U.S.
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