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BioWorld - Saturday, December 6, 2025
Home » Topics » Patents, BioWorld Science

Patents, BioWorld Science
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Cancer

Synnovation Therapeutics discovers new NRF2 inhibitors

Dec. 5, 2025
Synnovation Therapeutics Inc. has described heterocyclic compounds acting as nuclear factor erythroid 2-related factor 2 (NFE2-related factor 2; NFE2L2; NRF2) inhibitors reported to be useful for the treatment of cancer.
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Cancer

New FGFR3 inhibitors disclosed in Onco3r Therapeutics patent

Dec. 5, 2025
Onco3r Therapeutics BV has divulged fibroblast growth factor receptor 3 (FGFR3) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shandong Luye Pharmaceutical describes new salts of CDK2/cyclin E1 inhibitors

Dec. 5, 2025
Shandong Luye Pharmaceutical Co. Ltd. has identified salts of CDK2/cyclin E1 inhibitors reported to be useful for the treatment of cancer.
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Immuno-oncology

Lanova Medicines divulges new STn-targeting ADCs

Dec. 5, 2025
Lanova Medicines Ltd. has synthesized antibody-drug conjugates (ADCs) comprising antibodies targeting sialyl-Tn antigen (STn) linked to an exatecan derivative through a linker reported to be useful for the treatment of cancer.
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Cancer

Wigen Biomedicine patents new PI3Kα inhibitors

Dec. 5, 2025
Wigen Biomedicine Technology (Shanghai) Co. Ltd. has disclosed phosphatidylinositol 3-kinase α (PI3Kα) inhibitors reported to be useful for the treatment of solid cancers and hematological cancers.
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Neurology/psychiatric

Genescience discovers new salts of MC4 receptor antagonists

Dec. 4, 2025
Genescience Pharmaceuticals Co. Ltd. has described salts of known melanocortin MC4 receptor antagonists reported to be useful for the treatment of anorexia nervosa, cachexia, muscle atrophy, nausea and vomiting, sarcopenia, anxiety, bone disorders and inflammatory disorders.
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Cancer

AR degradation inducers disclosed in Qingdao Putaike Biomedical patent

Dec. 4, 2025
Qingdao Putaike Biomedical Technology Co. Ltd. has divulged hydrophobic tag-based degraders comprising heat shock protein 90 (HSP90) ligands covalently linked to an androgen receptor (AR)-targeting moiety through a linker acting as AR degradation inducers reported to be useful for the treatment of acne, androgenic alopecia, hirsutism, metabolic disorders, breast cancer and prostate cancer.
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Inflammatory

Chinese scientists describe new STING antagonists

Dec. 4, 2025
China Pharmaceutical University and Chongqing Innovation Institute, China Pharmaceutical University have identified compounds acting as stimulator of interferon genes protein (STING; TMEM173) antagonists reported to be useful for the treatment of cancer, fibrosis, infections, inflammation, autoimmune diseases, metabolic disorders, neurological disorders and cardiovascular disorders, among others.
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Cancer

Zhejiang Yangli Pharmaceutical Technology divulges new CDK2/cyclin E1 inhibitors

Dec. 4, 2025
Zhejiang Yangli Pharmaceutical Technology Co. Ltd. has synthesized thiazole-substituted pyrimidine amine compounds acting as CDK2/cyclin E1 inhibitors reported to be useful for the treatment of cancer.
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Cancer

Université de Montréal patents new GTPase KRAS inhibitors

Dec. 4, 2025
Université de Montréal has disclosed GTPase KRAS G12D mutant inhibitors reported to be useful for the treatment of cancer, inflammatory disorders and immunological disorders.
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