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BioWorld - Tuesday, May 5, 2026
Home » Topics » Patents, BioWorld Science

Patents, BioWorld Science
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Inflammatory

Shanghai Yidi Biotechnology describes new PDE4B2 and PDE4D2 inhibitors

Oct. 30, 2024
Shanghai Yidi Biotechnology Co. Ltd. has identified dihydrothienopyrimidine compounds acting as phosphodiesterase PDE4B2 and/or phosphodiesterase PDE4D2 inhibitors reported to be useful for the treatment of autoimmune disorders, metabolic diseases, neurological diseases and inflammatory disorders.
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Musculoskeletal

New GPR183 antagonists disclosed in Immunophage Biomedical patent

Oct. 30, 2024
Immunophage Biomedical Co. Ltd. has divulged G-protein coupled receptor 183 (GPR183; EBI2) antagonists reported to be useful for the treatment of autoimmune disease, cancer, liver diseases, osteoporosis and neuropathic pain.
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Cancer

Shanghai Huilun Pharmaceutical divulges new IRAK-4 degradation inducers

Oct. 30, 2024
Shanghai Huilun Pharmaceutical Co. Ltd. has synthesized proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin-protein ligase binding moiety coupled to an interleukin-1 receptor-associated kinase 4 (IRAK-4) targeting moiety through a linker reported to be useful for the treatment of cancer, neurodegeneration, infections, autoimmune disorders, metabolic diseases, cardiovascular disorders, genetic diseases and inflammatory disorders, among others.
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Cancer

Pfizer patents new compounds targeting GTPase KRAS

Oct. 30, 2024
Pfizer Inc. has disclosed drugs targeting GTPase KRAS and its mutant forms reported to be useful for the treatment of cancer.
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Endocrine/metabolic

FFA1 and FFA4 receptor agonists disclosed in Dartmouth College patent

Oct. 29, 2024
Dartmouth College has divulged fatty acid mimetics acting as free fatty acid FFA1 receptor (GPR40) and/or FFA4 receptor (GPR120) agonists reported to be useful for the treatment of obesity and type 2 diabetes.
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Infection

French scientists describe new conjugates for bacterial infections

Oct. 29, 2024
Scientists at Centre Hospitalier Regional Universitaire de Lille, Centre National de la Recherche Scientifique, Institut National De La Santé et de la Recherche Médicale, Institut Pasteur de Lille and Université de Lille have patented conjugates comprising siderophore moieties covalently linked to cargo moieties through a linker reported to be useful for the diagnosis and treatment of bacterial infections.
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Neurology/psychiatric

Biocells Biotech discovers new AQP4 inhibitors for cerebral ischemia

Oct. 29, 2024
Biocells (Beijing) Biotech Co. Ltd. has identified aquaporin-4 (AQP4) inhibitors reported to be useful for the treatment of cerebral ischemia.
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Cancer

National Institutes of Pharmaceutical R&D divulges new FGFR2 inhibitors

Oct. 29, 2024
National Institutes of Pharmaceutical R&D Co. Ltd. has synthesized fibroblast growth factor receptor 2 (FGFR2) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Baobab Aibio patents new YAP1/TEAD interaction inhibitors

Oct. 29, 2024
Baobab Aibio Co. Ltd. has disclosed transcriptional coactivator YAP1/transcriptional enhancer factor (TEAD) interaction inhibitors reported to be useful for the treatment of cancer.
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Cancer

Bivision Biomedical Technology discovers new radiolabeled-metal complexes targeting FAP

Oct. 28, 2024
Bivision Biomedical Technology (Nanjing) Co. Ltd. has described radiolabeled-metal complexes targeting fibroblast activation protein α (FAP) reported to be useful for the diagnosis and treatment of cancer.
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