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BioWorld - Thursday, June 25, 2026
Home » Topics » Patents, BioWorld Science

Patents, BioWorld Science
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Immune

Celgene discovers new PADI4 inhibitors

Dec. 19, 2023
Celgene Corp. has described heterocyclic protein-arginine deiminase type-4 (PADI4) inhibitors reported to be useful for the treatment of aging, autoimmune diseases, pain, asthma, inflammatory bowel diseases, AIDS, cancer and Alzheimer's disease, among others.
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Dermatologic

Samdolite Pharmaceuticals presents new prodrugs of cromoglicic acid

Dec. 19, 2023
Samdolite Pharmaceuticals LLC has divulged prodrugs of cromoglicic acid reported to be useful for the treatment of inflammation and dermatological disorders.
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Cancer

Sperogenix Therapeutics describes new Chk1 inhibitors

Dec. 19, 2023
Sperogenix Therapeutics Ltd. has identified nitrogen-containing five-membered heterocyclic derivatives acting as checkpoint kinase 1 (Chk1) inhibitors reported to be useful for the treatment of cancer, idiopathic pulmonary fibrosis and pulmonary arterial hypertension.
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Cancer

858 Therapeutics patents new PARG inhibitors for cancer

Dec. 19, 2023
858 Therapeutics Inc. has disclosed poly(ADP-ribose) glycohydrolase (PARG) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shanghai Meiyue Biotech Development describes new SIK2 inhibitors

Dec. 18, 2023
Shanghai Meiyue Biotech Development Co. Ltd. has identified serine/threonine-protein kinase SIK2 (QIK) inhibitors reported to be useful for the treatment of fibrosis, cancer, autoimmune diseases, transplant rejection, cardiovascular, dermatological, endocrine, and inflammatory disorders, among others.
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Cancer

Hangzhou Healthytide Biotechnology divulges new integrin α5β1 antagonists

Dec. 18, 2023
Hangzhou Healthytide Biotechnology Co. Ltd. has synthesized peptoids acting as integrin α5β1 (ITGA5; VLA-5) antagonists reported to be useful for the treatment of cancer and macular degeneration.
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Musculoskeletal

Dice Alpha patents new IL-17A inhibitors

Dec. 18, 2023
Dice Alpha Inc. has disclosed IL-17A inhibitors reported to be useful for the treatment of psoriasis, radiographic axial spondyloarthritis (ankylosing spondylitis), hidradenitis suppurativa, spondyloarthritis, psoriatic and rheumatoid arthritis.
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Neurology/Psychiatric

Xalud Therapeutics discovers new intercalating sugar molecules for pain, inflammation and autoimmune diseases

Dec. 15, 2023
Xalud Therapeutics Inc. has described conjugates comprising a sugar moiety covalently bonded to a DNA-interacting moiety through a linker reported to be useful for the treatment of pain, inflammation and autoimmune diseases, among others.
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Neurology/Psychiatric

Cypralis presents new cyclophilin A and cyclophilin D inhibitors

Dec. 15, 2023
Cypralis Ltd. has divulged macrocyclic compounds acting as peptidyl-prolyl cis-trans isomerase A (PPIA; cyclophilin A; CYPA) and/or cyclophilin D inhibitors reported to be useful for the treatment of multiple sclerosis and epilepsy.
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Cancer

Zhejiang Wenda Pharma Technology describes new HER2 and mutant inhibitors for cancer

Dec. 15, 2023
Zhejiang Wenda Pharma Technology Ltd. has identified HER2 (erbB2) and its (exon 20 insertion [Ex20Ins], (Ala775_Gly776insTyrValMetAla)) mutant inhibitors reported to be useful for the treatment of cancer.
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