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BioWorld - Thursday, April 30, 2026
Home » Topics » Patents, BioWorld Science

Patents, BioWorld Science
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Endocrine/metabolic

Genescience discovers new SLC6A19 inhibitors for PKU

Oct. 29, 2025
Genescience Pharmaceuticals Co. Ltd. has identified sodium-dependent neutral amino acid transporter B(0)AT1 (SLC6A19) inhibitors reported to be useful for the treatment of phenylketonuria (PKU).
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Cancer

Inventisbio divulges new PI3Kα inhibitors

Oct. 29, 2025
Inventisbio Co. Ltd. and Inventisbio LLC have synthesized phosphatidylinositol 3-kinase α (PI3Kα) E542K mutant inhibitors reported to be useful for the treatment of cancer, PIK3CA-related overgrowth spectrum (PROS) and congenital lipomatous overgrowth, vascular malformations, epidermal naevi and skeletal abnormalities (CLOVES syndrome).
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Cancer

China Resources Pharmaceutical Research Institute patents new PRMT5 inhibitors

Oct. 29, 2025
China Resources Pharmaceutical Research Institute (Shenzhen) Co. Ltd. has disclosed heterocyclic compounds acting as protein arginine N-methyltransferase 5 (PRMT5) inhibitors reported to be useful for the treatment of cancer.
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Ocular

Shenzhen Newrosetta Biosciences discovers new muscarinic M2 receptor antagonists

Oct. 28, 2025
Shenzhen Newrosetta Biosciences Co. Ltd. has described deuterated derivatives of AF-DX 116 acting as muscarinic M2 receptor antagonists reported to be useful for the treatment of myopia.
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Immuno-oncology

New antibody-drug conjugates disclosed in Wuxi XDC patent

Oct. 28, 2025
Scientists at Wuxi XDC (Shanghai) Co. Ltd. and Wuxi XDC Singapore Pvt Ltd. have divulged antibody-drug conjugates comprising antibodies covalently linked to cytotoxic drugs reported to be useful for the treatment of cancer.
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Cancer

Shenzhen Bay Laboratory describes new PKMYT1 inhibitors

Oct. 28, 2025
Shenzhen Bay Laboratory has identified Myt1 kinase (PKMYT1) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shenzhen Zhongge Biotechnology divulges new SMARCA2 inhibitors

Oct. 28, 2025
Shenzhen Zhongge Biotechnology Co. Ltd. has synthesized probable global transcription activator SNF2L2 (SMARCA2; BAF190B; SNF2-α) inhibitors reported to be useful for the treatment of cancer.
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Musculoskeletal

Chinese scientists patent new DDR1 inhibitors

Oct. 28, 2025
Shanghai Institute of Materia Medica of the Chinese Academy of Sciences has disclosed discoidin domain-containing receptor 1 (DDR1) inhibitors reported to be useful for the treatment of systemic lupus erythematosus and rheumatoid arthritis.
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Endocrine/metabolic

Suzhou Spring-Sea Bio-Pharmaceuticals discovers new GLP-1R, GCGR and GIPR agonists

Oct. 27, 2025
Suzhou Spring-Sea Bio-Pharmaceuticals Co. Ltd. has described polypeptides acting as glucagon-like peptide 1 receptor (GLP-1R), glucagon receptor (GCGR) and gastric inhibitory polypeptide receptor (GIPR) agonists reported to be useful for the treatment of dyslipidemia, hepatic steatosis, metabolic syndrome, obesity and type 2 diabetes.
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Cancer

New TEAD1 degradation inducers disclosed in Amphista patent

Oct. 27, 2025
Amphista Therapeutics Ltd. has divulged proteolysis targeting chimera (PROTAC) compounds comprising an F-Box only protein 22 (FBXO22)-binding moiety coupled to a transcriptional enhancer factor TEF (TEAD)-targeting moiety through a linker reported to be useful for the treatment of cancer.
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