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BioWorld - Wednesday, July 1, 2026
Home » Topics » Patents, BioWorld Science

Patents, BioWorld Science
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Inflammatory

Chinese scientists describe new STING antagonists

Dec. 4, 2025
China Pharmaceutical University and Chongqing Innovation Institute, China Pharmaceutical University have identified compounds acting as stimulator of interferon genes protein (STING; TMEM173) antagonists reported to be useful for the treatment of cancer, fibrosis, infections, inflammation, autoimmune diseases, metabolic disorders, neurological disorders and cardiovascular disorders, among others.
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Cancer

Zhejiang Yangli Pharmaceutical Technology divulges new CDK2/cyclin E1 inhibitors

Dec. 4, 2025
Zhejiang Yangli Pharmaceutical Technology Co. Ltd. has synthesized thiazole-substituted pyrimidine amine compounds acting as CDK2/cyclin E1 inhibitors reported to be useful for the treatment of cancer.
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Cancer

Université de Montréal patents new GTPase KRAS inhibitors

Dec. 4, 2025
Université de Montréal has disclosed GTPase KRAS G12D mutant inhibitors reported to be useful for the treatment of cancer, inflammatory disorders and immunological disorders.
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Cancer

Shenzhen Forward Pharmaceuticals discovers new FGFR2 inhibitors

Dec. 3, 2025
Shenzhen Forward Pharmaceuticals Co. Ltd. has described fibroblast growth factor receptor 2 (FGFR2) inhibitors reported to be useful for the treatment of stomach cancer and intrahepatic cholangiocarcinoma.
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Cancer

New TP53 stabilizers disclosed in Shanghai Qilu Pharmaceutical patent

Dec. 3, 2025
Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. has divulged cellular tumor antigen p53 (TP53) (Tyr220Cys mutant) stabilizers reported to be useful for the treatment of cancer.
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Infection

Zhimeng Biopharma describes new compounds to treat HBV infection

Dec. 3, 2025
Zhimeng Biopharma has identified compounds reported to be useful for the treatment of hepatitis B viral (HBV) infection.
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Endocrine/metabolic

Chinese scientists divulge new XOR inhibitors

Dec. 3, 2025
Apichope Bio Pharmaceutical Co. Ltd., Apichope Pharmaceutical Co. Ltd., Guangzhou Lianrui Pharmaceutical Co. Ltd. and Guangzhou Runlin Pharmaceutical Technology Co. Ltd. have synthesized xanthine dehydrogenase/oxidase (XDH; XOR) inhibitors reported to be useful for the treatment of hyperuricemia, gout, arthritis and heart failure.
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Cancer

Canadian scientists patent new peptide-drug conjugates

Dec. 3, 2025
Theratechnologies Inc. and Transfert Plus SEC have disclosed peptide-drug conjugates comprising a maytansinoid moiety linked to peptides targeting the sortilin (neurotensin NTR3; NT3; Gp95) receptor through a protease-cleavable linker reported to be useful for the treatment of cancer.
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Musculoskeletal

Alebund Pharmaceuticals discovers new complement factor B inhibitors

Dec. 2, 2025
Alebund Pharmaceuticals (Hong Kong) Ltd. has described complement factor B (CFB) inhibitors reported to be useful for the treatment of glomerular disorders and rheumatoid arthritis.
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Cancer

New CDK inhibitors disclosed in Adlai Nortye patent

Dec. 2, 2025
Adlai Nortye Biopharma Co. Ltd. and Adlai Nortye Pte Ltd. have divulged cyclin-dependent kinase 2 (CDK2) and/or CDK4 and/or CDK6 inhibitors reported to be useful for the treatment of inflammatory disorders, immunological disorders and cancer.
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