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BioWorld - Saturday, December 20, 2025
Home » Topics » Patents, BioWorld Science

Patents, BioWorld Science
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Dermatologic

Samsung Life Public Welfare Foundation discovers new TLR signaling inhibitors

Nov. 26, 2025
Samsung Life Public Welfare Foundation has described peptides acting as Toll-like receptor (TLR) signaling inhibitors and antioxidants reported to be useful for the treatment of cancer as well as immunological, dermatological and inflammatory disorders.
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Immune

New SIK inhibitors disclosed in Insilico Medicine patent

Nov. 26, 2025
Insilico Medicine IP Ltd. has divulged serine/threonine-protein salt-inducible kinase (SIK) inhibitors reported to be useful for the treatment of autoimmune disease, cancer, metabolic diseases, transplant rejection, and cardiovascular, dermatological, inflammatory and respiratory disorders, among others.
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Cancer

Chengdu Chipscreen Pharmaceutical describes new Mat2A inhibitors

Nov. 26, 2025
Chengdu Chipscreen Pharmaceutical Ltd. has identified S-adenosylmethionine synthase isoform type-2 (Mat2A) inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Biohaven Therapeutics divulges new PKM2 activators

Nov. 26, 2025
Biohaven Therapeutics Ltd. has synthesized pyruvate kinase M2 (PKM2) activators reported to be useful for the treatment of age-related macular degeneration, amyotrophic lateral sclerosis, multiple sclerosis, retinitis pigmentosa and fibrosis.
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Cancer

Nikang Therapeutics patents new CDK2 and CDK4 degradation inducers

Nov. 26, 2025
Nikang Therapeutics Inc. has disclosed proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase-binding moiety coupled to a cyclin-dependent kinase 2 (CDK2)- and/or CDK4-targeting moiety through a linker reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Chinese scientists discover new NMDA receptor antagonists

Nov. 25, 2025
Researchers at Shanghai Institute of Materia Medica of the Chinese Academy of Sciences and Suzhou Vigonvita Life Sciences Co. Ltd. have described NMDA receptor antagonists and/or monoamine transporter inhibitors reported to be useful for the treatment of neurological disorders.
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Cancer

PRMT5 inhibitors disclosed in Shanghai Apeiron Biotechnology patent

Nov. 25, 2025
Shanghai Apeiron Biotechnology Co. Ltd. has divulged protein arginine N-methyltransferase 5 (PRMT5) inhibitors reported to be useful for the treatment of brain metastatic cancer.
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Cancer

Université de Montréal describes new SRC and YES1 inhibitors

Nov. 25, 2025
Université de Montréal has identified compounds acting as proto-oncogene tyrosine-protein kinase Src (SRC; SRC1) and/or tyrosine-protein kinase Yes (YES1) inhibitors reported to be useful for the treatment of cancer, fibrosis and liver diseases.
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Cancer

Nanjing Synnocare Pharmaceutical divulges new KIF18A inhibitors

Nov. 25, 2025
Nanjing Synnocare Pharmaceutical Technology Co. Ltd. has synthesized prodrugs of kinesin-like protein KIF18A inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Captor Therapeutics patents new Nek7 degradation inducers

Nov. 25, 2025
Captor Therapeutics Inc. has disclosed molecular glue degraders comprising a cereblon (CRBN) binding moiety acting as serine/threonine-protein kinase Nek7 degradation inducers reported to be useful for the treatment of amyotrophic lateral sclerosis, Still’s disease, Behçet’s disease, familial Mediterranean fever, Alzheimer’s disease, pulmonary arterial hypertension and more.
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