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BioWorld - Tuesday, December 30, 2025
Home » Topics » Patents, BioWorld Science

Patents, BioWorld Science
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Cardiovascular

Boehringer Ingelheim discovers new STING antagonists

Nov. 20, 2025
Boehringer Ingelheim Pharma GmbH & Co KG has described stimulator of interferon genes protein (STING; TMEM173) antagonists reported to be useful for the treatment of glaucoma, rheumatoid arthritis, heart failure, sepsis, interstitial lung diseases, nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH), bloom syndrome and cancer.
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Neurology/psychiatric

New Nav1.8 blockers disclosed in Hengrui patent

Nov. 20, 2025
Jiangsu Hengrui Pharmaceuticals Co. Ltd. and Shanghai Hengrui Pharmaceutical Co. Ltd. have divulged aromatic compounds acting as sodium channel protein type 10 subunit α (SCN10A; Nav1.8) blockers reported to be useful for the treatment of pain.
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Cancer

Sunrise Oncology describes new PDE3A/SLFN12 interaction inducers

Nov. 20, 2025
Sunrise Oncology (Hong Kong) Ltd. has identified molecular glues acting as phosphodiesterase PDE3A/SLFN12 interaction inducers reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Shandong Quanzhong unveils monoamine transmitter reuptake inhibitors

Nov. 20, 2025
Shandong Quanzhong Biomedical Technology Co. Ltd. has synthesized monoamine transmitter reuptake inhibitors reported to be useful for the treatment of neurological disorders, depression, autism, pain, substance abuse and dependency, epilepsy, osteoporosis and metabolic diseases, among others.
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Cancer

Hangzhou Baicreat Pharma-Tech patents new STAT6 inhibitors

Nov. 20, 2025
Hangzhou Baicreat Pharma-Tech Co. Ltd. has disclosed oxamide compounds acting as signal transducer and activator of transcription 6 (STAT6) inhibitors reported to be useful for the treatment of cancer and inflammatory disorders.
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Infection

Zhuhai United Laboratories discovers new β-lactamase inhibitors

Nov. 19, 2025
Zhuhai United Laboratories Co. Ltd. has described β-lactamase (bacterial) inhibitors reported to be useful for the treatment of bacterial infections.
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Cancer

New GSPT1/CSNK1A1 degradation inducers disclosed in Mindrank patent

Nov. 19, 2025
Mindrank Therapeutics (Suzhou) New Drug Research & Development Co. Ltd. has divulged molecular glue degraders comprising cereblon (CRBN) ligands acting as dual eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) and casein kinase 1 isoform α (CSNK1A1) degradation inducers. They are reported to be potentially useful for the treatment of cancer, Alzheimer’s disease, inflammatory disorders, autoimmune diseases and metabolic diseases.
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Immuno-oncology

Hutchmed describes new antibody-drug conjugates

Nov. 19, 2025
Hutchmed Ltd. has identified antibody-drug conjugates comprising an antibody or antigen binding fragment covalently linked to a GTPase RAS or KRAS inhibitor through a linker reported to be useful for the treatment of cancer.
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Cancer

Hangzhou Zhongmei Huadong Pharmaceutical divulges new GTPase KRAS inhibitors

Nov. 19, 2025
Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd. has synthesized GTPase KRAS wild-type and/or its mutant inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Yichang Humanwell Pharmaceutical patents new κ-opioid receptor agonists

Nov. 19, 2025
Yichang Humanwell Pharmaceutical Co. Ltd. has disclosed morphinan derivatives acting as κ-opioid receptor agonists reported to be useful for the treatment of pain and pruritus.
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