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BioWorld - Sunday, June 28, 2026
Home » Topics » Regulatory » Patents

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Musculoskeletal

Genescience Pharmaceuticals describes new FGFR2 and FGFR3 inhibitors

Dec. 18, 2024
Genescience Pharmaceuticals Co. Ltd. has identified fibroblast growth factor receptor 2 (FGFR2) and/or FGFR3 inhibitors reported to be useful for the treatment of cancer, osteochondrodysplasia and achondroplasia.
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Cancer

Quantx Biosciences US discovers new PARG inhibitors

Dec. 18, 2024
Quantx Biosciences US Inc. has described poly(ADP-ribose) glycohydrolase (PARG) inhibitors reported to be useful for the treatment of cancer.
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Cancer

New TLR7 and TLR8 agonists disclosed in Roche patent

Dec. 18, 2024
Scientists at F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have divulged compounds acting as Toll-like receptor 7 (TLR7) and TLR8 agonists reported to be useful for the treatment of cancer.
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Cardiovascular

Chia Tai Tianqing Pharmaceutical divulges new NTCP inhibitors

Dec. 18, 2024
Chia Tai Tianqing Pharmaceutical Group Co. Ltd. has synthesized sodium-bile acid cotransporter (SLC10A1; NTCP) inhibitors reported to be useful for the treatment of cardiovascular, fatty acid oxidation, liver and gastrointestinal disorders.
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Inflammatory

Insilico Medicine patents new NLRP3 inflammasome inhibitors

Dec. 18, 2024
Insilico Medicine Inc. has disclosed NLRP3 inflammasome inhibitors reported to be useful for the treatment of autoimmune and inflammatory disorders.
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Neurology/psychiatric

Shanghai Institute of Organic Chemistry discovers new LRRK2 inhibitors

Dec. 17, 2024
Shanghai Institute of Organic Chemistry has described leucine-rich repeat kinase 2 (LRRK2; dardarin) inhibitors reported to be useful for the treatment of cancer, autoimmune diseases, inflammatory disorders, Parkinson’s disease and Alzheimer’s disease, among others.
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Cancer

New protein kinase inhibitors disclosed in Magicbullet patent

Dec. 17, 2024
Magicbullet Therapeutics Inc. has divulged protein kinase inhibitors reported to be useful for the treatment of cancer.
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Ocular

Lento Bio divulges new cysteine derivatives for presbyopia

Dec. 17, 2024
Lento Bio Inc. has synthesized cysteine derivatives reported to be useful for the treatment of presbyopia. An exemplified compound (Cpd in row 4 in tbl1 pg 20, claim 18) decreased in lens stiffness in C57BL/6 mice (at 20 mM; as eye drops).
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Cancer

Iregene Therapeutics describes new BMPR1B inhibitors

Dec. 17, 2024
Iregene Therapeutics (Suzhou) Co. Ltd. has identified pyrazolecarbonyl piperazinone compounds acting as bone morphogenetic protein receptor type-1B (BMPR1B) inhibitors reported to be useful for the treatment of cancer and pulmonary hypertension.
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Cancer

Circle Pharma patents new CDK inhibitors

Dec. 17, 2024
Circle Pharma Inc. has disclosed cyclin-dependent kinase (CDK) inhibitors reported to be useful for the treatment of cancer.
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