BEIJING – China will kickstart a phase III trial Feb. 3 to determine whether patients with 2019-nCoV can be treated with Gilead Sciences Inc.’s NUC inhibitor, remdesivir, which was originally developed for Ebola, four days after a U.S. patient was said to have recovered by using the drug candidate.
BioWorld looks at translational medicine, including: Adapting NGS for coronavirus surveillance; Long QT genes mostly short on evidence; Reservoir dogs don’t hunt; Another reason to get a flu shot; Cerebrospinal fluid is early culprit in stroke edema; Different drivers can turn the wheel in glioblastoma’s vicious cycle; From African genomes, big insights with small sample size; Commercial antibodies underwhelm for studies of PP2A; Tau keeps gliomas in check.
BEIJING – The current speed of new developments in the 2019-nCov outbreak is illustrated by a Jan. 28, 2020, press conference in Munich, where Andreas Zapf, head of the infection task force in the Bavarian ministry for health and food safety, briefed reporters on the first confirmed German case.
Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Aspen, Curevac, Follicum, Fuzionaire, ICER, Nanoviricides, Novartis, Predictive Oncology, Quantitative Medicine, Saromics, Vaxart, Ziopharm.
The World Health Organization (WHO) has declared a "public health emergency of international concern" over the global outbreak of novel coronavirus (2019-nCoV), reversing a week-ago decision by its International Health Regulations Emergency Committee. The move comes "not because of what is happening in China, but because of what is happening in other countries," said WHO Director General Tedros Adhanom Ghebreyesus, noting his confidence in China’s capacity to control the outbreak. "Our greatest concern is the potential for the virus to spread to countries with weaker health systems, and which are ill-prepared to deal with it," he said.
Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Advaccine, Allergan, Aptinyx, BGI, Biocorrx, Cortexyme, Curetis, Dare, Evotec, Histogen, Inovio, Iteos, Theraly, Tonix.
LONDON – It has gone from “pneumonia of unknown cause” affecting 44 patients in Wuhan, China, on Jan. 5, 2020, to spark a global health alert, with the World Health Organization (WHO) now looking likely to declare the outbreak of the novel coronavirus, 2019-nCoV, a public health emergency of international concern (PHEIC) less than four weeks later.
Despite pressure from several lawmakers to declare the new coronavirus a U.S. public health emergency, Health and Human Services (HHS) Secretary Alex Azar said such a declaration isn’t needed, at least not yet.
HONG KONG – As drug developers are racing to find a cure for the new coronavirus, researchers in Hong Kong claim to have made major headway in the development of a vaccine for the virus that has so far killed 132. Yuen Kwok-yung, the chair of infectious diseases at the University of Hong Kong’s (HKU) department of microbiology, said in a press briefing at Hong Kong’s Queen Mary Hospital that his team had successfully isolated the novel virus from the first imported case in Hong Kong. But he said the vaccine still needs months to be tested on animals and an additional year for human trials before it is fit for use.
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