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BioWorld - Tuesday, December 30, 2025
Home » Topics » Infection » Coronavirus

Coronavirus
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Recbio’s COVID-19 vaccine shows strong efficacy in phase II Philippines trial

Dec. 28, 2022
By Doris Yu
Jiangsu Recbio Technology Co. Ltd. released phase II data showing its recombinant two-component COVID-19 vaccine Recov appeared more effective than Comirnaty (tozinameran), the mRNA vaccine developed by Biontech SE and Pfizer Inc., as a booster for users of inactivated vaccines.
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Regulatory actions for Dec. 28, 2022

Dec. 28, 2022
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Genentech, Intercept, Ipsen, Janux, Kaken, Leo, Mediwound, Mindrank AI, Neuren, Neurocrine, Nova Mentis, Regeneron, Revive, Springworks, Valneva, Zielbio.
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In the clinic for Dec. 28, 2022

Dec. 28, 2022
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Acasti, Bioxytran, Can-Fite, Clene, PDS.
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Infection

3C-like proteinase (Mpro) inhibitors described in Pardes Biosciences patent

Dec. 28, 2022
Pardes Biosciences Inc. has patented 3C-like proteinase (3CLpro; Mpro; nsp5) inhibitors (particularly HCoV-229E virus and/or SARS-CoV-2 Mpro inhibitors). They are reported to be potentially useful for the treatment of SARS-CoV-2 infections (COVID-19).
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Regulatory actions for Dec. 27, 2022

Dec. 27, 2022
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Acer, Adaptimmune, Antengene, Basilea, Biogen, Brainstorm, Celltrion, Coherus, Daiichi Sankyo, DBV, Deka, Disc, Eisai, Elpiscience, Immutep, Junshi, Kite, Relief.
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In the clinic for Dec. 27, 2022

Dec. 27, 2022
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Applied Molecular Transport, Atai, Biontech, Cellectis, Dilafor, Immunis, Jiangsu Recbio, Karolinska, Kures, Nanobiotix, Neuren.
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SARS-CoV-2 virus particles
Infection

Genetically attenuated SARS-CoV-2 protects against pneumonia in Syrian hamster model of COVID-19

Dec. 27, 2022
Eleven vaccines have now been approved by the World Health Organization for preventing COVID-19, but all exhibit drastically reduced activities after 6 months. Unlike vaccines that express only the spike protein as the immunogen, live attenuated vaccines have the potential to confer a broader and more durable protection.
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Colorized transmission electron micrograph of SARS-CoV-2 (UK B.1.1.7 variant).
Immune

Oragenics reports toxicology findings with NT-CoV2-1 intranasal COVID-19 vaccine candidate

Dec. 23, 2022
Oragenics Inc. has announced results from its...
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Colorful illustration of the heart

Neuome Peptides develops platform to detect cardiovascular diseases

Dec. 22, 2022
By Zhang Mengying
A new acute coronary syndrome detection system developed by Neuome Peptides Pte. Ltd.’s aims to make tests for the frequently lethal condition faster, more precise and less invasive. Neuome’s Truheart is a point-of-care assay for cardiovascular disease that is used in the company’s established Instadetect assay development platform. The assay measures the biomarkers troponins I and T and myoglobin.
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Regulatory actions for Dec. 22, 2022

Dec. 22, 2022
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Abivax, Actinogen, ADC, Affimed, Akebia, Aldeyra, Alnylam, Alvotech, Aquestive, Astrazeneca, Benevolentai, Edesa, Genentech, Genmab, Gilead, Gradalis, Iaso, Innocare, Merck, Mirati, Onkyo, Outlook, Pfizer, Radius, Regenxbio, Sanofi, Sobi.
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