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BioWorld - Friday, May 8, 2026
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BioWorld Science, Cancer
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Stem cells
Cancer

Shinobi gets grants, investments for up to $127M

Aug. 7, 2024
Shinobi Therapeutics Inc. has been awarded non-dilutive grant funding of up to $59 million by the Japanese Agency for Medical Research and Development (AMED).
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CAR T cells attacking cancer cell
Immuno-oncology

ROBO1 CAR T cells fight tumors and metastases in brain

Aug. 7, 2024
Investigators at McMaster University have developed a CAR T cell that targeted roundabout guidance receptor 1 (ROBO1).
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Cancer

Tiumbio synthesizes pyrazolopyrimidine derivatives as CDK9 inhibitors

Aug. 7, 2024
Tiumbio Co. Ltd. has prepared and tested cyclin-dependent kinase 9 (CDK9) inhibitors reported to be useful for the treatment of cancer, inflammation and fibrosis.
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Cancer

Risen Pharma identifies new PROTACS for KRAS-driven cancers

Aug. 6, 2024
Risen (Shanghai) Pharma Eng Co. Ltd. and Risen (Suzhou) Pharma Tech Co. Ltd. have divulged proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding agents coupled to GTPase KRAS or its mutant targeting moiety through a linker reported to be useful for the treatment of cancer.
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Cancer

Jacobio Pharmaceuticals patents TP53 mutant stabilizers

Aug. 6, 2024
Jacobio Pharmaceuticals Co. Ltd. has prepared and tested cellular tumor antigen p53 (TP53) (Y220C mutant) stabilizers reported to be useful for the treatment of cancer.
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Multiple myeloma illustration
Cancer

Fibroblast growth factor traps have anti-myeloma activity

Aug. 6, 2024
Researchers from the University of Brescia have presented the discovery and preclinical characterization of novel fibroblast growth factor (FGF) trap small molecules, being developed for the treatment of multiple myeloma (MM).
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Eye wireframe illustration
Biomarkers

RBMS1 is prognostic biomarker in ocular melanoma

Aug. 6, 2024
Researchers from Shanghai Jiao Tong University and affiliated organizations have presented data from a study that aimed to identify the prognostic markers related to abnormal methylation in ocular melanoma, including uveal melanoma (UM).
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Cancer

Incyte divulges heteroaryl fluoroalkenes as DGK inhibitors

Aug. 5, 2024
Incyte Corp. has synthesized diacylglycerol kinase α (DGK-α) and/or diacylglycerol kinase ζ (DGK-ζ) inhibitors reported to be useful for the treatment of cancer.
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Cancer

IFM Due identifies mutant-selective EGFR inhibitors

Aug. 5, 2024
IFM Due Inc. has disclosed EGFR (HER1; erbB1) mutant inhibitors reported to be useful for the treatment of cancer.
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Cancer

Angel Pharmaceuticals presents new PARP-7 inhibitors

Aug. 5, 2024
Angel Pharmaceuticals Co. Ltd. has described protein mono-ADP-ribosyltransferase TIPARP (PARP-7; ARTD14) inhibitors reported to be useful for the treatment of cancer.
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