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BioWorld - Sunday, May 17, 2026
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Home » Topics » BioWorld Science, Neurology/psychiatric

BioWorld Science, Neurology/psychiatric
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DNA illustration
Neurology/psychiatric

Kate Therapeutics reports on DMD gene therapy candidate

May 17, 2024
Kate Therapeutics Inc. recently presented data on a novel muscle- and heart-targeted, liver de-targeted development candidate for the treatment of Duchenne muscular dystrophy (DMD) – KT-809.
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Excitatory (pyramidal) neurons colored by size.
Neurology/psychiatric

Full reconstruction of brain tissue block gives insights into structure, function

May 17, 2024
By Mar de Miguel
A group of scientists from Harvard University have observed and reconstructed the human brain at the resolution of the electron microscope, with all its cells, following all the connections between its neurons around a cubic millimeter of a tissue sample. They took 10 years and the data occupies 1.4 petabytes (1,400 terabytes). However, they are already planning a bigger project.
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Neurology/psychiatric

Beijing Tide Pharmaceutical reports new orydalmine derivatives

May 15, 2024
Beijing Tide Pharmaceutical Co. Ltd. has described orydalmine derivatives reported to be useful for the treatment of pain, depression, and substance abuse and dependence.
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Neurology/psychiatric

MSD describes new Kv3.1 potassium channel modulators

May 14, 2024
Merck Sharp & Dohme LLC has patented potassium voltage-gated channel subfamily C member 1 (Kv3.1; KCNC1) activators reported to be useful for the treatment of neurological and psychiatric disorders.
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Silhouettes
Neurology/psychiatric

Preclinical data support 4M Therapeutics’ GSK-3β inhibitors for treatment of bipolar disorder and acute mania

May 14, 2024
4M Therapeutics Inc. has announced the presentation of preclinical data on its small-molecule glycogen synthase kinase-3β (GSK-3β) inhibitors in models of bipolar disorder.
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Neurology/psychiatric

PR-009, a new AAV-hTREM2 gene therapy to restore microglial function in patients with ALSP-CSF1R

May 14, 2024
Macrophage colony-stimulating factor 1 receptor (CSF-1R) is a transmembrane tyrosine kinase receptor expressed in brain microglia, and mutations in the CSF1R gene have been linked to adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP).
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Neurology/psychiatric

Tisento Therapeutics identifies new sGC activators

May 13, 2024
A Tisento Therapeutics Inc. patent describes new soluble guanylate cyclase (sGC) activators reported to be useful for the treatment of Alzheimer’s and Parkinson’s diseases, vascular dementia, ischemic stroke, Leigh syndrome, Pearson syndrome, creatine deficiency syndrome and Alpers syndrome, among others.
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Neurology/psychiatric

Norwegian University of Science and Technology divulges new CSF-1R inhibitors

May 10, 2024
Norwegian University of Science and Technology (NTNU) has synthesized macrophage colony-stimulating factor 1 receptor (CSF-1R; CD115; c-Fms) inhibitors reported to be useful for the treatment of cancer, amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, macular degeneration, osteoarthritis, osteoporosis, rheumatoid arthritis and Alzheimer’s disease, among others.
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Microscope with beakers and flasks
Drug design, drug delivery & technologies

Avicenna extends machine learning platform to enhance medicinal chemistry

May 9, 2024
Avicenna Biosciences Inc. has introduced an extension to its machine learning (ML) technology platform to enhance medicinal chemistry and expedite clinical-stage drug discovery.
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Neurology/psychiatric

Kissei Pharmaceutical presents new orexin OX2 receptor agonists for narcolepsy

May 8, 2024
Kissei Pharmaceutical Co. Ltd. has divulged orexin OX2 receptor agonists reported to be useful for the treatment of narcolepsy.
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