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BioWorld - Thursday, July 16, 2026
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Home » Topics » BioWorld Science, Neurology/psychiatric

BioWorld Science, Neurology/psychiatric
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Neurology/Psychiatric

Harmony Biosciences enters licensing agreement with Bioprojet for OX2 receptor agonist

April 12, 2024
Harmony Biosciences Holdings Inc. has announced an exclusive licensing agreement with Bioprojet Pharma SAS to develop, manufacture and commercialize TPM-1116, a highly potent and selective oral orexin OX2 receptor agonist that will be evaluated for the treatment of narcolepsy and other sleep/wake disorders.
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Neurology/Psychiatric

Lundbeck and Vernalis present new LRRK2 and LRRK2 G2019S mutant inhibitors

April 11, 2024
Scientists at H. Lundbeck A/S and Vernalis (R&D) Ltd. have divulged leucine-rich repeat kinase 2 (LRRK2; Dardarin) and LRRK2 G2019S mutant inhibitors reported to be useful for the treatment of Parkinson’s disease, Lewy body dementia and multiple system atrophy.
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The calcitonin gene related peptide (CGRP, yellow) bound to its receptor
Dermatologic

Neuropeptide released by pain neurons promotes wound healing by interacting with immune system

April 11, 2024
By Subhasree Nag
Wound healing is a highly specialized dynamic process for the repair of damaged/injured tissues through an intricate mechanism. Any failure in the normal wound healing process results in abnormal scar formation, and a chronic state which is more susceptible to infections. Researchers from Monash University in Australia and Osaka University in Japan have demonstrated that the removal of a specific subtype of sensory neurons containing the Nav1.8+ ion channel significantly impairs skin wound repair and muscle regeneration following injury.
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Neurology/Psychiatric

Cerevel Therapeutics discovers new muscarinic M4 receptor agonists

April 10, 2024
Cerevel Therapeutics LLC has described muscarinic M4 receptor agonists reported to be useful for the treatment of pain, sleep disorder, schizophrenia, substance abuse and dependence, drug-induced dyskinesia, Alzheimer’s disease and Parkinson’s disease.
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Neurology/Psychiatric

Vanderbilt University patents new mGlu5 receptor negative allosteric modulators

April 10, 2024
Vanderbilt University has disclosed mGlu5 receptor negative allosteric modulators reported to be useful for the treatment of anxiety, autism spectrum disorders, diabetes, pain, Parkinson’s disease, multiple sclerosis, depression and obesity, among others.
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Illustration of brain with electrical activity background
Neurology/Psychiatric

Teijin Pharma grants Bioprojet rights to OX2 receptor agonist for narcolepsy

April 10, 2024
Teijin Pharma Ltd. has entered into an exclusive global licensing agreement with Bioprojet under which Teijin Pharma grants Bioprojet Pharma SAS exclusive worldwide rights to research, develop, manufacture and commercialize an investigational candidate for narcolepsy.
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Neurology/Psychiatric

Benevolentai divulges new RARα and RARβ agonists

April 9, 2024
Benevolentai Cambridge Ltd. has synthesized retinoid acid receptor α (RARα) and β (RARβ) agonists reported to be useful for the treatment of cancer and amyotrophic lateral sclerosis (ALS).
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Silhouette made of gears
Neurology/Psychiatric

Mina Therapeutics and Nippon Shinyaku partner on RNAa therapeutics for neurodegenerative diseases

April 5, 2024
Mina Therapeutics Ltd. has announced a research collaboration and licensing agreement option with Nippon Shinyaku Co. Ltd. for the discovery and potential development and commercialization of small activating RNA (RNAa) therapeutic candidates targeting rare neurodegenerative diseases for which there are currently no treatment options.
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Neurology/Psychiatric

Nanjing Zhongrui Medicine discovers new protein phosphatase 2A activators for Alzheimer’s disease

April 5, 2024
Nanjing Zhongrui Medicine Co. Ltd. has described protein phosphatase 2A (PP2A) activators reported to be useful for the treatment of Alzheimer’s disease.
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Brain
Neurology/Psychiatric

Inmed reports new preclinical data on INM-901 for Alzheimer’s disease

April 5, 2024
Inmed Pharmaceuticals Inc. has reported new preclinical data demonstrating INM-901’s pharmacological effects for the potential treatment of Alzheimer’s disease. Several preclinical studies were conducted in well-characterized Alzheimer’s disease models.
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