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BioWorld - Sunday, August 2, 2026
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BioWorld Science, Patents
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Ocular

Shenzhen Bay Laboratory describes new compounds for aldehyde metabolism disorders

Sep. 29, 2025
Shenzhen Bay Laboratory has identified compounds reported to be useful for the treatment of cancer, eye, cardiovascular, metabolic, autoimmune, inflammatory, neurological and dermatological disorders.
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Gynecology/obstetrics

Genescience Pharmaceuticals divulges new 17β-HSD1 inhibitors

Sep. 29, 2025
Genescience Pharmaceuticals Co. Ltd. has synthesized sterols acting as estradiol 17-β-dehydrogenase 1 (HSD17B1; 17β-HSD1) inhibitors reported to be useful for the treatment of endometriosis.
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Gastrointestinal

Daewon Pharm patents new reversible H+/K+-ATPase inhibitors

Sep. 29, 2025
Daewon Pharm Co. Ltd. has disclosed tricyclic derivatives acting as reversible H+/K+-ATPase inhibitors reported to be useful for the treatment of gastroesophageal reflux disease.
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Cancer

Ileadbms patents new SOS1/GTPase KRAS interaction inhibitors

Sep. 26, 2025
Ileadbms Co. Ltd. has described son of sevenless homolog 1 (SOS1)/GTPase KRAS G12D mutant interaction and SOS1/GTPase KRAS G12C mutant interaction inhibitors reported to be useful for the treatment of cancer, arteriovenous malformations, cardiofaciocutaneous syndrome, Costello syndrome and more.
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Cancer

Shattuck Labs presents new TRIM7 inhibitors

Sep. 26, 2025
Shattuck Labs Inc. has divulged oligopeptides acting as E3 ubiquitin-protein ligase TRIM7 (GNIP; RNF90) inhibitors reported to be useful for the treatment of cancer, infections and inflammatory disorders.
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Neurology/psychiatric

Hager Biosciences discloses new antagonists of orexin and κ-opioid receptors

Sep. 26, 2025
Hager Biosciences LLC has identified orexin receptor and/or κ-opioid receptor dual antagonists reported to be useful for the treatment of cancer, psychiatric, neurological and cardiovascular disorders.
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Cancer

Bristol Myers Squibb discovers new TLR7 agonists

Sep. 26, 2025
Bristol Myers Squibb Co. has patented Toll-like receptor 7 (TLR7) agonists reported to be useful for the treatment of cancer.
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Endocrine/metabolic

The Scripps Research Institute describes new GLP-1R/GIPR dual agonists

Sep. 26, 2025
The Scripps Research Institute has disclosed peptides and their drug conjugates acting as dual gastric inhibitory polypeptide receptor (GIPR) and glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of diabetes, metabolic dysfunction-associated steatotic liver disease and obesity.
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Cancer

Nanjing Nuoyuan Medical Devices identifies new fluorescent probe

Sep. 25, 2025
Nanjing Nuoyuan Medical Devices Co. Ltd. has discovered drug conjugates comprising a fluorescent moiety targeting hepatocyte growth factor receptors (HGFR; MET) covalently linked to crizotinib through a linker. They are reported to be useful for diagnosis of liver and colon cancer.
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Neurology/psychiatric

Neushen Therapeutics synthesizes new NLRP3 inflammasome inhibitors

Sep. 25, 2025
Neushen Therapeutics Inc. has patented NLRP3 inflammasome inhibitors reported to be useful for the treatment of Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, amyotrophic lateral sclerosis and Huntington’s disease.
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