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BioWorld - Saturday, December 6, 2025
Breaking News: Trump administration impacts continue to roil the life sciences sectorBreaking News: ASH 2025: Casgevy for kids? Expanding, improving SCD gene therapiesBreaking News: Trump administration impacts continue to roil the life sciences sectorBreaking News: Trump administration impacts continue to roil the life sciences sector
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BioWorld Science, Patents
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Cancer

Shenzhen Forward Pharmaceuticals discovers new FGFR2 inhibitors

Dec. 3, 2025
Shenzhen Forward Pharmaceuticals Co. Ltd. has described fibroblast growth factor receptor 2 (FGFR2) inhibitors reported to be useful for the treatment of stomach cancer and intrahepatic cholangiocarcinoma.
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Cancer

New TP53 stabilizers disclosed in Shanghai Qilu Pharmaceutical patent

Dec. 3, 2025
Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. has divulged cellular tumor antigen p53 (TP53) (Tyr220Cys mutant) stabilizers reported to be useful for the treatment of cancer.
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Infection

Zhimeng Biopharma describes new compounds to treat HBV infection

Dec. 3, 2025
Zhimeng Biopharma has identified compounds reported to be useful for the treatment of hepatitis B viral (HBV) infection.
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Endocrine/metabolic

Chinese scientists divulge new XOR inhibitors

Dec. 3, 2025
Apichope Bio Pharmaceutical Co. Ltd., Apichope Pharmaceutical Co. Ltd., Guangzhou Lianrui Pharmaceutical Co. Ltd. and Guangzhou Runlin Pharmaceutical Technology Co. Ltd. have synthesized xanthine dehydrogenase/oxidase (XDH; XOR) inhibitors reported to be useful for the treatment of hyperuricemia, gout, arthritis and heart failure.
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Cancer

Canadian scientists patent new peptide-drug conjugates

Dec. 3, 2025
Theratechnologies Inc. and Transfert Plus SEC have disclosed peptide-drug conjugates comprising a maytansinoid moiety linked to peptides targeting the sortilin (neurotensin NTR3; NT3; Gp95) receptor through a protease-cleavable linker reported to be useful for the treatment of cancer.
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Musculoskeletal

Alebund Pharmaceuticals discovers new complement factor B inhibitors

Dec. 2, 2025
Alebund Pharmaceuticals (Hong Kong) Ltd. has described complement factor B (CFB) inhibitors reported to be useful for the treatment of glomerular disorders and rheumatoid arthritis.
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Cancer

New CDK inhibitors disclosed in Adlai Nortye patent

Dec. 2, 2025
Adlai Nortye Biopharma Co. Ltd. and Adlai Nortye Pte Ltd. have divulged cyclin-dependent kinase 2 (CDK2) and/or CDK4 and/or CDK6 inhibitors reported to be useful for the treatment of inflammatory disorders, immunological disorders and cancer.
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Cancer

Chengdu Chipscreen Pharmaceutical describes new WRN inhibitors

Dec. 2, 2025
Chengdu Chipscreen Pharmaceutical Ltd. has identified Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Abbisko Therapeutics divulges new SMARCA2 inhibitors

Dec. 2, 2025
Abbisko Therapeutics Co. Ltd. has synthesized probable global transcription activator SNF2L2 (SMARCA2; BAF190B; SNF2-α) inhibitors reported to be useful for the treatment of cancer.
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Endocrine/metabolic

Chinese researchers patent new URAT1 inhibitors

Dec. 2, 2025
Apichope Pharmaceutical Co. Ltd., Guangzhou Lianrui Pharmaceutical Co. Ltd. and Guangzhou Runlin Pharmaceutical Technology Co. Ltd. have disclosed solute carrier family 22 member 12 (SLC22A12; URAT1) inhibitors reported to be useful for the treatment of hyperuricemia, nephropathy and gout.
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