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BioWorld - Thursday, January 22, 2026
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BioWorld Science, Patents
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Ocular

Guangzhou Runer Ophthalmic Biotechnology describes new complement factor B inhibitors

Dec. 31, 2025
Guangzhou Runer Ophthalmic Biotechnology Co. Ltd. has identified complement factor B (CFB) inhibitors reported to be useful for the treatment of age-related macular degeneration, asthma, atherosclerosis, Crohn’s disease, glomerular disorders, hemolytic uremic syndrome, neurological disorders and diabetic retinopathy, among others.
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Cancer

Shanghai Xianxiang Medical Technology patents new CDK2/cyclin E1 inhibitors

Dec. 31, 2025
Shanghai Xianxiang Medical Technology Co. Ltd. has synthesized CDK2/cyclin E1 inhibitors reported to be useful for the treatment of cancer.
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Immuno-oncology

Hainan Simcere Pharmaceutical divulges new antibody-drug conjugates

Dec. 31, 2025
Hainan Simcere Pharmaceutical Co. Ltd. has disclosed antibody-drug conjugates comprising a glycoengineered antibody covalently linked to a cytotoxic drug through a linker reported to be useful for the treatment of cancer.
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Nephrology

Huayao Jiyuan (Shenzhen) Pharmaceutical discovers new HIF-2α inhibitors

Dec. 30, 2025
Huayao Jiyuan (Shenzhen) Pharmaceutical Co. Ltd. has described hypoxia inducible factor-2α (HIF-2α; EPAS1) inhibitors reported to be useful for the treatment of cancer, infections, cardiovascular disorders, anemia, chronic kidney disease, disorders of hematopoiesis, inflammatory disorders and acute respiratory distress syndrome (ARDS).
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Neurology/psychiatric

New Nav1.8 blockers disclosed in Chengdu Easton Biopharmaceuticals patent

Dec. 30, 2025
Chengdu Easton Biopharmaceuticals Co. Ltd. has divulged sodium channel protein type 10 subunit α (SCN10A; Nav1.8) blockers reported to be useful for the treatment of pain, arrhythmia, cough, urinary incontinence and multiple sclerosis.
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Gastrointestinal

Insilico Medicine describes new SIK inhibitors

Dec. 30, 2025
Insilico Medicine Inc. has identified serine/threonine-protein salt-inducible kinases (SIK) inhibitors reported to be useful for the treatment of rheumatoid arthritis, nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH), giant cell arteritis, primary sclerosing cholangitis, inflammatory bowel disease, atherosclerosis, type 2 diabetes and glomerulonephritis, among others.
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Neurology/psychiatric

Neurodawn Pharmaceutical divulges new PDE3A inhibitors

Dec. 30, 2025
Neurodawn Pharmaceutical Co. Ltd. has synthesized phosphodiesterase PDE3A inhibitors reported to be useful for the treatment of dementia and cerebrovascular disorders.
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Cancer

Guangzhou Institutes of Biomedicine and Health patents new BRD4 BD2 inhibitors

Dec. 30, 2025
Guangzhou Institutes of Biomedicine and Health has disclosed bromodomain-containing protein 4 (BD2 domain) (BRD4 BD2) inhibitors reported to be useful for the treatment of diabetes, autoimmune diseases, cardiovascular disorders, male contraception, chronic obstructive pulmonary disease, viral and parasitic infections and cancer.
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Endocrine/metabolic

Fortvita Biologics discovers new GLP-1R agonists

Dec. 29, 2025
Fortvita Biologics Inc. has described glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of autoimmune diseases, cardiovascular disorders, inflammatory disorders, diabetes, lung diseases, neurological disorders, obesity and renal disorders, among others.
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Infection

New DHODH inhibitors for malaria disclosed in patent

Dec. 29, 2025
Medicines for Malaria Venture and The University of Texas System have divulged dihydroorotate dehydrogenase (DHODH) (Plasmodium falciparum and Plasmodium vivax) inhibitors reported to be useful for the treatment of malaria.
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