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BioWorld - Sunday, February 22, 2026
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BioWorld Science, Patents
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Neurology/psychiatric

Yuhan patents new TREM2 agonists

Feb. 12, 2026
Yuhan Corp. has disclosed triggering receptor expressed on myeloid cells 2 (TREM2) agonists described as potentially useful for the treatment of neurological disorders.
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Inflammatory

Shenzhen Salubris Pharma identifies new IL-17A inhibitors

Feb. 12, 2026
Shenzhen Salubris Pharmaceuticals Co. Ltd. has synthesized interleukin-17A (IL-17A) inhibitors reported to be useful for the treatment of arthritis and psoriasis.
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Cancer

Voronoi discovers new MET inhibitors

Feb. 12, 2026
Voronoi Inc. has divulged hepatocyte growth factor receptor (HGFR; c-MET) inhibitors. They are reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Sundance Biosciences synthesizes new TYK2 inhibitors

Feb. 12, 2026
Sundance Biosciences Inc. has discovered non-receptor tyrosine-protein kinase TYK2 inhibitors potentially useful for the treatment of multiple sclerosis.
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Cancer

MSD and Otsuka Pharma report new TP53 Y220C mutant stabilizers

Feb. 12, 2026
Scientists from Merck Sharp & Dohme LLC and Otsuka Pharmaceutical Co. Ltd. have identified cellular tumor antigen p53 (TP53) Y220C mutant stabilizers reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Aquinnah Pharmaceuticals patents MAPT aggregation inhibitors

Feb. 11, 2026
Aquinnah Pharmaceuticals Inc. has disclosed new microtubule-associated protein τ (PHF-τ; MAPT) aggregation inhibitors designed for use in the treatment of Alzheimer’s disease and frontotemporal dementia.
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Cancer

Kunshan Xinyunda Biotechnology synthesizes new ADCs

Feb. 11, 2026
Kunshan Xinyunda Biotechnology Co. Ltd. has discovered antibody-drug conjugates (ADCs) consisting of antibodies covalently linked to cytotoxic drugs potentially useful for the treatment of cancer.
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Nephrology

Chinese researchers discover new SLC22A12 inhibitors

Feb. 11, 2026
Scientists from Shenzhen Medical Academy of Research and Translation and the Southern Medical University have synthesized solute carrier family 22 member 12 (SLC22A12; URAT1) inhibitors. They are reported to be useful for the treatment of kidney injury, hyperuricemia and gout.
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Cancer

Bivision Pharma reports new cyclic peptides targeting FAP

Feb. 11, 2026
Bivision Pharmaceuticals (Shanghai) Co. Ltd. has identified cyclic peptides targeting fibroblast activating protein α (FAP) reported to be useful for the treatment of cancer.
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Cancer

Brazilian scientists identify new HDAC6 inhibitors

Feb. 11, 2026
Researchers from Eurofarma Laboratorios SA and Universidade Federal do Rio de Janeiro – Macae havs synthesized histone deacetylase 6 (HDAC6) inhibitors reported to be potentially useful for the treatment of cancer.
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