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BioWorld - Thursday, December 18, 2025
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Cancer

Zhongshan Innovation New Drug Development discovers new conjugates to diagnose and treat cancer

Nov. 7, 2025
Zhongshan Innovation New Drug Development Co. Ltd. has described conjugates comprising a chelating ligand moiety, a fibroblast activation protein α (FAP) ligand and integrin αvβ3 or integrin αvβ6 ligand and a linker. They are reported to be potentially useful for the diagnosis and/or treatment of cancer.
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Infection

Agents for Acinetobacter infections named in Chinese Academy of Medical Sciences patent

Nov. 7, 2025
Chinese Academy of Medical Sciences has divulged imidazopyridine derivatives reported to be useful for the treatment of Acinetobacter infections, particularly A. baumannii infections.
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Cancer

Chengdu Zeling Biomedical Technology describes new PARP-1 inhibitors

Nov. 7, 2025
Chengdu Zeling Biomedical Technology Co. Ltd. has identified salts of deuterated compounds acting as poly(ADP-ribose) polymerase 1 (PARP-1; ARTD1) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Simcere Pharmaceutical divulges new STAT6 degradation inducers

Nov. 7, 2025
Simcere Pharmaceutical Co. Ltd. has synthesized proteolysis targeting chimeras (PROTACs) comprising E3 ubiquitin-protein ligands coupled to a signal transducer and activator of transcription 6 (STAT6)-targeting moiety via a linker reported to be useful for the treatment of cancer and inflammatory disorders.
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Diagnostics

Bivision Pharmaceuticals patents new radiolabeled conjugates

Nov. 7, 2025
Bivision Pharmaceuticals (Shanghai) Co. Ltd. has disclosed peptide-drug conjugates reported to be useful for diagnosis and treatment of fibrosarcoma.
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Hematologic

Simcere Pharmaceutical discovers new plasminogen activators

Nov. 6, 2025
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Simcere Pharmaceutical Co. Ltd. has described stachybotrys microspore triprenyl phenols (SMTPs) acting as plasminogen activators reported to be useful for the treatment of thromboembolism.
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Immune

Pentacyclic derivatives for autoimmune diseases disclosed in Hansoh patent

Nov. 6, 2025
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Jiangsu Hansoh Pharmaceutical Group Co. Ltd. and Shanghai Hansoh Biomedical Co. Ltd. have divulged pentacyclic derivatives reported to be useful for the treatment of autoimmune disease.
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Cancer

Hangzhou Raygene Pharmaceutical describes new benzotriazine dioxide compounds

Nov. 6, 2025
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Hangzhou Raygene Pharmaceutical Co. Ltd. has identified benzotriazine dioxide compounds reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Chinese scientists divulge new Nav1.8 blockers

Nov. 6, 2025
No Comments
Scientists at Apichope Bio Pharmaceutical Co. Ltd., Apichope Pharmaceutical Co. Ltd., Guangzhou Lianrui Pharmaceutical Co. Ltd. and Guangzhou Runlin Pharmaceutical Technology Co. Ltd. have synthesized sodium channel protein type 10 subunit α (SCN10A; Nav1.8) blockers potentially useful for the treatment of pain, arrhythmia, cough, multiple sclerosis, urinary incontinence and Charcot-Marie-Tooth disease.
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Cancer

Scinnohub patents new RET inhibitors

Nov. 6, 2025
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Scinnohub Pharmaceutical Co. Ltd. has disclosed compounds reported to be useful for the treatment of cancer and inflammatory diseases.
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