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BioWorld - Saturday, May 24, 2025
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Home » Topics » BioWorld Science, Patents

BioWorld Science, Patents
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Cancer

Marsal Therapeutics discovers new compounds to treat glioblastoma multiforme

April 8, 2025
Marsal Therapeutics Inc. has described compounds reported to be useful for the treatment of glioblastoma multiforme (GBM).
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Gastrointestinal

New LPAM-1 antagonists for IBD disclosed in Morphic patent

April 8, 2025
Morphic Therapeutic Inc. has divulged integrin α4β7 (LPAM-1) antagonists reported to be useful for the treatment of inflammatory bowel disease (IBD).
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Infection

Gilead Sciences describes new nucleoside prodrugs for viral infections

April 8, 2025
Gilead Sciences Inc. has identified nucleoside prodrugs reported to be useful for the treatment of viral infections.
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Cancer

Impact Therapeutics divulges new PARP-1 inhibitors

April 8, 2025
Impact Therapeutics Inc. has synthesized poly(ADP-ribose) polymerase 1 (PARP-1; ARTD1) inhibitors reported to be useful for the treatment of neurologic cancer.
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Cancer

Newave Pharmaceutical patents new GTPase KRAS inhibitors

April 8, 2025
Newave Pharmaceutical LLC has disclosed GTPase KRAS (mutant) inhibitors reported to be useful for the treatment of cancer, autoimmune disease and inflammatory disorders.
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Infection

NSTDA discovers new viral replication inhibitors

April 7, 2025
National Science & Technology Development Agency (NSTDA) has described cordycepin derivatives acting as viral replication inhibitors reported to be useful for the treatment of viral infections.
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Cancer

New EGFR Ex20Ins mutant inhibitors disclosed in Roche patent

April 7, 2025
Scientists at F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have divulged prop-2-ynamide derivatives acting as EGFR (Exon 20 insertion [Ex20Ins] mutant) inhibitors reported to be useful for the treatment of cancer, in particular non-small-cell lung cancer (NSCLC).
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Neurology/psychiatric

Insilico Medicine describes new PSD-95 protein inhibitors

April 7, 2025
Insilico Medicine Ltd. has identified postsynaptic density-95 (PSD-95) protein inhibitors acting as neuroprotective agents reported to be useful for the treatment of epilepsy, anxiety disorders, neurodegeneration, neuropathic pain, stroke and cerebral infarction.
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Cancer

Shanghai Helioson Pharmaceutical divulges new GSPT1 degradation inducers

April 7, 2025
Shanghai Helioson Pharmaceutical Co. Ltd. has synthesized molecular glue degraders comprising an E3 ubiquitin ligase coupled to a eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) targeting moiety acting as GSPT1 degradation inducers reported to be useful for the treatment of cancer.
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Cancer

Gilead Sciences patents new GTPase KRAS inhibitors

April 7, 2025
Gilead Sciences Inc. has disclosed GTPase KRAS (G12D mutant) inhibitors reported to be useful for the treatment of cancer.
Read More
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