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BioWorld - Wednesday, June 3, 2026
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Home » Topics » BioWorld Science, Patents

BioWorld Science, Patents
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Cancer

Hangzhou Baicreat Pharma-Tech describes new PTPN1 and PTPN2 inhibitors

Dec. 16, 2025
Hangzhou Baicreat Pharma-Tech Co. Ltd. has identified tyrosine-protein phosphatase non-receptor type 1 (PTPN1; PTP-1B) and/or tyrosine-protein phosphatase non-receptor type 2 (PTPN2; TCPTP) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Onco3r Therapeutics divulges new TP53 stabilizers

Dec. 16, 2025
Onco3r Therapeutics BV has synthesized cellular tumor antigen p53 (TP53) Y220C mutant stabilizers reported to be useful for the treatment of cancer.
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Immuno-oncology

Genome Therapeutics patents new compounds and immunoconjugates

Dec. 16, 2025
Genome Therapeutics Ltd. has disclosed compounds and their immunoconjugates comprising an antibody covalently linked to a cytotoxic drug through a linker reported to be useful for the treatment of cancer.
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Cancer

Apollo AP45 discovers new PERK inhibitors

Dec. 15, 2025
Apollo AP45 Ltd. has described eukaryotic translation initiation factor 2-α kinase 3 (PERK) inhibitors reported to be useful for the treatment of cancer.
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Cancer

New KIF18A inhibitors disclosed in Inventisbio patent

Dec. 15, 2025
Inventisbio Co. Ltd. and Inventisbio LLC have divulged kinesin-like protein KIF18A inhibitors reported to be useful for the treatment of cancer.
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Respiratory

Minova Pharmaceutical and Precision Brain Science describe new salts of deuterated dextromethorphan

Dec. 15, 2025
Nanjing Minova Pharmaceutical Co. Ltd. and Precision Brain Science Biotechnology (Suzhou) Co. Ltd. have identified salts of deuterated dextromethorphan reported to be useful for the treatment of cough, pain, epilepsy, cancer, rheumatoid arthritis, dermatitis, cardiovascular disorders and glaucoma.
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Cancer

Chinese researchers divulge new WRN inhibitors

Dec. 15, 2025
Shanghai Aryl Pharmtech Co. Ltd. and Zhejiang Hisun Pharmaceutical Co. Ltd. have synthesized aza-tricyclic derivatives acting as Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shenzhen Targetrx patents new Bcr-Abl1 degradation inducers

Dec. 15, 2025
Shenzhen Targetrx Inc. has disclosed proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase-binding moiety covalently linked to a Bcr-Abl (Bcr-Abl1) kinase and its mutant targeting moiety through a linker reported to be useful for the treatment of cancer and immunological disorders.
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Endocrine/metabolic

Hansoh discovers new GIPR, GCGR and GLP-1R agonists

Dec. 12, 2025
Jiangsu Hansoh Pharmaceutical Group Co. Ltd. and Shanghai Hansoh Biomedical Co. Ltd. have described compounds acting as gastric inhibitory polypeptide receptor (GIPR), glucagon receptor (GCGR) and glucagon-like peptide-1 receptor (GLP-1R) agonists reported to be useful for the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD, NAFLD), diabetes and obesity.
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Respiratory

Chengdu Sibeibo Pharmaceutical Technology discloses new Hedgehog signaling inhibitors and SMO antagonists

Dec. 12, 2025
Chengdu Sibeibo Pharmaceutical Technology Co. Ltd. has divulged deuterated derivatives of taladegib acting as Hedgehog signaling inhibitors and protein smoothened (SMO) antagonists reported to be useful for the treatment of cancer and idiopathic pulmonary fibrosis.
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