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CD38 inhibitors discovered at Napa Therapeutics, Buck Institute

May 6, 2022

Silverback Therapeutics synthesizes TGFR-1 inhibitors and antibody-drug conjugates

May 6, 2022

Enliven Therapeutics describes new Bcr-Abl kinase inhibitors

May 6, 2022

BCY-6033: EphA2-targeting BTC with efficacy in NSCLC PDX models

May 6, 2022

Researchers discover HDAC1 as the cause of immune abnormalities in autistic mouse models

May 5, 2022

DGKk gene therapy rescues brain lipid profiles and long-term behavior in fragile X syndrome mice

May 5, 2022

ALTA-2530 shows preclinical efficacy as potential treatment of bronchiolitis obliterans syndrome

May 5, 2022

FDA awards orphan drug designation to AB-001 for pancreatic cancer and AML

May 5, 2022

CDK7 inhibitor GTAEXS-617 shows potent antitumor activity in vivo

May 5, 2022

TRAIL protein levels may predict response to acamprosate in alcohol use disorder

May 5, 2022

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Today's news in brief
BioWorld
BioWorld briefs for Jan 30, 2025.
Today's news in brief
Briefs
BioWorld MedTech briefs for Jan. 30, 2026.
Centessa’s CNT-9982 shows promise for MDD
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Orexin OX2 receptor agonists have demonstrated the ability to enhance wakefulness in rodent models, as well as in nonhuman primates and patients with narcolepsy...
First-in-class ADC targeting DEM-TXX shows high preclinical efficacy
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Researchers at DEM Biopharma Inc. reported preclinical findings demonstrating the efficacy of DEM-301, a bifunctional antibody-drug conjugate (ADC) engineered to...
5-HT2R allosteric ligands attenuate cocaine use and seeking behavior
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Serotonergic G-protein-coupled receptors (GPCRs), including the 5-HT2A receptor (5-HT2AR) and 5-HT2CR, are key regulators of cortical signaling pathways and...