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Idorsia Pharmaceuticals patents CCR6 antagonists

Nov. 24, 2021

ALTA-002, a Toll-like receptor agonist antibody conjugate with promising antitumor activity in vivo

Nov. 24, 2021

GNE-502 shows promising efficacy in breast tumor xenograft model

Nov. 24, 2021

SNS-101, an anti-VISTA antibody, potentiates anti-PD-1/PD-L1 antitumor immunity

Nov. 24, 2021

Researchers develop a nonhuman primate model of Parkinson's disease

Nov. 24, 2021

Sanyou presents SYZJ-001 bispecific antibody drug against COVID-19

Nov. 23, 2021

Guard reports preclinical data on ROSgard in animal models of sepsis

Nov. 23, 2021

KAND-145 + cisplatin reduces tumor size in disease model of chemotherapy-resistant ovarian cancer

Nov. 23, 2021

Erythrocyte miR-210 as target for prevention of endothelial dysfunction in type 2 diabetes

Nov. 23, 2021

Bristol Myers Squibb adds structurally diverse compounds to BET inhibitor candidates

Nov. 23, 2021

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Centessa’s CNT-9982 shows promise for MDD
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Orexin OX2 receptor agonists have demonstrated the ability to enhance wakefulness in rodent models, as well as in nonhuman primates and patients with narcolepsy...
First-in-class ADC targeting DEM-TXX shows high preclinical efficacy
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Researchers at DEM Biopharma Inc. reported preclinical findings demonstrating the efficacy of DEM-301, a bifunctional antibody-drug conjugate (ADC) engineered to...
5-HT2R allosteric ligands attenuate cocaine use and seeking behavior
BioWorld Science
Serotonergic G-protein-coupled receptors (GPCRs), including the 5-HT2A receptor (5-HT2AR) and 5-HT2CR, are key regulators of cortical signaling pathways and...