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Leptin affects T-cell metabolism

Nov. 25, 2019

NASH progression tied to redox state

Nov. 25, 2019

Discovery of targetable dopamine receptor controlling childhood-onset asthma

Nov. 25, 2019

CLCA1-TMEM16A-chloride current pathway mediates renal injury in aging and diabetes

Nov. 25, 2019

Phase I data presented for TPI-287 in Alzheimer's disease and 4-repeat tauopathies

Nov. 25, 2019

Klotho shows potential as therapeutic target in podocyte injury of diabetic nephropathy

Nov. 25, 2019

Hepatic YBX1 as a novel therapeutic target for obesity-related liver disorders

Nov. 25, 2019

Upadacitinib demonstrates promising safety and efficacy in phase II/III SELECT-AXIS 1 study

Nov. 25, 2019

Study shows TINCR lncRNA overexpression in epithelial ovarian cancer and role in tumor progression

Nov. 25, 2019

Inhibiting bradykinin B1 receptor may alleviate hypertensive kidney disease

Nov. 22, 2019

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MMP inhibitors divulged in Accure Therapeutics patent
BioWorld Science
Accure Therapeutics has reported new oligopeptide derivatives acting as matrix metalloproteinase-2 (MMP-2) and MMP-9 inhibitors. As such, they are described as...
MSD discloses new HCN1/2 blockers
BioWorld Science
Merck Sharp & Dohme LLC (MSD) has synthesized new indazole derivatives acting as potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1...
Orexin OX2 receptor agonists disclosed in Vertex Pharmaceuticals patent
BioWorld Science
Vertex Pharmaceuticals Inc. has patented new macrocyclic sulfonamide orexin OX2 receptor agonists potentially useful for the treatment of amyotrophic lateral...