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BioWorld - Saturday, February 21, 2026
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In the clinic for Aug. 20, 2024

Aug. 20, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Latigo, Mindbio.
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Appointments and advancements for Aug. 20, 2024

Aug. 20, 2024
New hires and promotions in the biopharma industry, including: 89bio, Actio, Atossa, Avenacy, Cidara, Corbus, Incyclix, Latigo, Pepgen.
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Illustration of influenza virus replication complex with chicken, cow, human, seal wireframe drawings
Infection

Structural study gives insights into influenza virus species jumps

Aug. 20, 2024
By Anette Breindl
“There are hundreds of strains of bird flu, and most of them don’t infect humans, or even mammals,” Stephen Cusack told BioWorld. “There are two main reasons for that.” To be able to cause an infection, a virus “has to be able to get into the cell, and for that it needs a receptor,” Cusack said. For influenza viruses, those receptors are hemagglutinin receptors, and they differ in subtle but important ways between birds and mammals.
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Heart and lungs

Tentative approval of Yutrepia still leaves Liquidia adrift

Aug. 19, 2024
By Lee Landenberger
Despite the U.S. FDA’s tentative approval of Liquidia Corp.’s Yutrepia (treprostinil) for treating pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease, the company is stuck in the starting gate. Liquidia said it disagrees with the agency’s stance of simultaneously granting regulatory exclusivity in both indications to United Therapeutics Corp.’s powdered formulation of treprostinil, branded Tyvaso, until May 23, 2025. That means full approval for the inhalation powder won’t come until after that date and neither will a Yutrepia launch.
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Stocks rise along with concerns of global mpox outbreak

Aug. 19, 2024
By Jennifer Boggs
Following the World Health Organization’s escalation of mpox to a public health emergency of international concern on Aug. 14 and the emergence of what appears to be a more severe strain of the orthopoxvirus, the spotlight has focused on a handful of companies working on vaccines and antivirals. Shares of Geovax Labs Inc., Emergent Biosolutions Inc. and Tonix Pharmaceuticals Inc. were all trading up Aug. 19.
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Alzamend phase II with ‘new’ lithium: PTSD near critical Mass?

Aug. 19, 2024
By Randy Osborne
A week after the U.S. FDA spurned Lykos Therapeutics Inc.’s bid for approval of a therapy in post-traumatic stress disorder (PTSD), shares of Alzamend Neuro Inc. (NASDQ:ALZN) zoomed upward on more news in the indication with a next-generation, cocrystal lithium compound AL-001. Atlanta-based Alzamend’s stock closed Aug. 19 at $5.85, up $3.82, or 188%.
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Global handshake silhouette

Huadong gets China rights to Imbiologics’ Oxtima program for ₩430B

Aug. 19, 2024
By Marian (YoonJee) Chu
Imbiologics Inc. scored a potential ₩430 billion (US$315.5 million) deal with China’s Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd. for Oxtima, an autoimmune disease program with two assets co-developed by Seoul, South Korea-based HK Inno.N Corp.
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Australia flag with microscope, test tubes

Pfizer urges Australia to establish clear vision for life sciences

Aug. 19, 2024
By Tamra Sami
Pfizer Inc. is calling on the Australian government to establish priorities for the life sciences sector to attract more investment into research, clinical trials and manufacturing in Australia. The new report recommends that the government issue a life sciences vision akin to the one issued by the U.K. in 2021 to make the country more competitive to attract investment.
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Other news to note for Aug. 19, 2024

Aug. 19, 2024
Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Alera Pharma, Biomotion, Boston Immune, Eli Lilly, Lobe Sciences, Lykos, Moringa, Morphic, Otsuka, Silexion.
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Regulatory actions for Aug. 19, 2024

Aug. 19, 2024
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Astellas, Astrazeneca, Bavarian Nordic, Deciphera, Mediwound, Ono, Theramex.
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