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BioWorld - Saturday, December 13, 2025
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Novel coronavirus SARS-CoV-2

SARS-CoV-2 infection of neurons; no ACE2 required

July 21, 2022
By Mar de Miguel
Since the isolation of SARS-CoV-2 and the study of its infection mechanisms, scientists have been trying to understand how this virus accesses the brain and produces neurological symptoms.
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Researchers in lab demonstrating technology

New monitor may help surgeons detect blood clots faster

July 1, 2022
By David Godkin
The University of Central Florida (UCF) and Orlando Health are testing new medical technology designed to identify blood clots more quickly in surgery. The monitoring device consists of a small optical fiber that uses red blood cells to track the process of blood coagulation in patients so doctors can watch for life threatening blood clot formation.
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Red blood cells

Long in the making changes lead to tipping point in blood stem cells

June 3, 2022
By Nuala Moran
Two studies published back to back in Nature have looked at the accumulation of mutations in blood-forming stem cells with age, gaining new insights into how the overall landscape of such cells changes across the lifespan. 
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Cancer cell and DNA

To escape radiation, tumor cells reversibly damage their DNA

May 2, 2022
By Nuala Moran
Researchers have uncovered a new pathway via which cancer cells evade the effects of radiation by deploying self-inflicted – but reversible – DNA breaks to stop the cell cycle and ensure their survival. The lesions are caused by caspase-activated DNase (CAD), an enzyme involved in DNA fragmentation during cell death. In response to radiation, tumor cells activate CAD, causing genome-wide DNA breaks at sites involved in DNA repair.
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Multiple sclerosis

Study finds targets of T-cell response in multiple sclerosis

April 28, 2022
By Anette Breindl
Screening a panel of potential autoantigens, investigators at the Karolinska Institute have identified four autoantigens that are targeted by the T cells of multiple sclerosis patients.
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Human anatomy

Sex disparities of lupus recapitulated in mouse model

April 25, 2022
By Anette Breindl
A new animal model of systemic lupus erythematosus (lupus) could be useful for understanding the disparity of the disorder, which is vastly more common in women than men.
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Cross section of brain

Deep brain stimulation of central thalamus restores consciousness in primate models

April 22, 2022
By Bernard Banga
A research team led by neuroscientists and neurosurgeons from Paris-Saclay University have recently managed to demonstrate that electrical stimulation of the thalamus can restore consciousness when this has been impaired.
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Vega system

Vega 3-mouse ultrasound scan may accelerate preclinical drug development studies

April 19, 2022
By David Godkin
Perkinelmer Inc. said the Vega is a first-of-its-kind preclinical ultrasound system that will accelerate preclinical research and drug development studies of cancer, cardiovascular, liver, kidney and other diseases. The imaging platform combines hands-free automation with high-throughput capability, which the company said is a major advance over manual ultrasound scanning across the bodies of individual lab mice.
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Gloved hand puts samples in portable testing device

Hong Kong researchers develop portable COVID-19 testing device

April 18, 2022
By Zhang Mengying
An interdisciplinary research team from the Hong Kong Polytechnic University has developed a portable testing device that can detect the COVID-19 virus within 40 minutes.
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Red blood cells and coronavirus

ACE2-independent blood cell infection linked to severe COVID

April 7, 2022
By Anette Breindl
Investigators at Boston Children's Hospital have demonstrated that SARS-CoV-2 infection of blood monocytes and lung macrophages in the lung could kill the cells via pyroptosis, increasing inflammation and leading to severe COVID-19.
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