Last week s new deal between Aradigm Corp. and existing partner United Therapeutics Corp. through its wholly owned subsidiary Lung Rx Inc. to develop Remodulin (treprostinil) using the former s AERx Essence approach could provide the needed boost to put prostacyclins at the forefront of pulmonary arterial hypertension therapy (PAH), thanks to the metered-dose inhaler.
Cardiome Pharma Corp.'s strong Phase III data in June with intravenous vernakalant for atrial fibrillation (AF) or atrial flutter after coronary artery bypass graft (CABG) surgery may have opened the door for off-label use in new-onset AF, and also may have cleared a somewhat smoother regulatory path for the product. (BioWorld Financial Watch)
