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BioWorld - Friday, December 26, 2025
Home » Authors » Brian Orelli

Articles by Brian Orelli

Global drug spending to slow, will still exceed $1.5T by 2023

Feb. 6, 2019
By Brian Orelli
The global pharmaceutical market will surpass $1.5 trillion by 2023, according to a new report from Iqvia Institute for Human Data Science. That works out to a compounded annual growth rate of 3 percent to 6 percent over the next five years, which is, unfortunately, a slowdown from the 6.3 percent growth the industry has experienced over the past five years.
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Global drug spending to slow, will still exceed $1.5T by 2023

Feb. 5, 2019
By Brian Orelli

The global pharmaceutical market will surpass $1.5 trillion by 2023, according to a new report from Iqvia Institute for Human Data Science. That works out to a compounded annual growth rate of 3 percent to 6 percent over the next five years, which is, unfortunately, a slowdown from the 6.3 percent growth the industry has experienced over the past five years.


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Looking to long-term data for 'Rescue' after Gensight gene therapy disappoints

Feb. 5, 2019
By Brian Orelli
Bernard Gilly, co-founder and CEO of Gensight Biologics SA, was upbeat about the readout of Gensight's phase III Rescue study testing its gene therapy, GS-010, in patients with 11778-ND4 Leber hereditary optic neuropathy (LHON).
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Global drug spending to slow, will still exceed $1.5T by 2023

Feb. 4, 2019
By Brian Orelli
The global pharmaceutical market will surpass $1.5 trillion by 2023, according to a new report from Iqvia Institute for Human Data Science. That works out to a compounded annual growth rate of 3 percent to 6 percent over the next five years, which is, unfortunately, a slowdown from the 6.3 percent growth the industry has experienced over the past five years.
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Lyndra nabs $55M series B to support long-acting therapies

Jan. 30, 2019
By Brian Orelli

Lyndra nabs $55M series B to support long-acting therapies

Jan. 30, 2019
By Brian Orelli
Following up on its 2017 $23.5 million series A financing, Lyndra Therapeutics Inc. secured $55 million in a series B round to support the development of its long-acting therapies. All of the previous investors resubscribed, while Hopu Investments, Gilead Sciences Inc., Invus, the Bill & Melinda Gates Foundation and Orient Life joined their ranks. (See BioWorld Today, April 14, 2017.)
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Trevena looks to relieve pain of oliceridine CRL

Jan. 29, 2019
By Brian Orelli
Trevena Inc. had a painful end to 2018 with the FDA's Anesthetic and Analgesic Drug Products Advisory Committee voting 7-8 against recommending the proposed 0.1-mg and 0.35-mg doses of oliceridine, followed by a complete response letter (CRL) from the FDA the subsequent month.
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'Notable' development scheme: donate drug, collect voucher

Jan. 28, 2019
By Brian Orelli
About four years after starting up as part of the Y Combinator accelerator, Notable Labs Inc. has its first drug, ND-1000, ready to enter the clinic.
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'Notable' development scheme: donate drug, collect voucher

Jan. 28, 2019
By Brian Orelli
About four years after starting up as part of the Y Combinator accelerator, Notable Labs Inc. has its first drug, ND-1000, ready to enter the clinic.
Read More

Apic Bio secures $40M to fund silence & replace gene therapy

Jan. 8, 2019
By Brian Orelli
Gene therapy has come a long way since the initial treatments of the early 1990s, but the insertion of genes can't help diseases with toxic gain-of-function mutations. Apic Bio Inc. is looking to overcome that limitation with its gene therapy platform, Thrive, which includes a second component expressing an miRNA to silence toxic gain-of-function mutations from a single vector.
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