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BioWorld - Wednesday, April 15, 2026
Home » Authors » Brian Orelli

Articles by Brian Orelli

Use of CROs continues to grow, but companies remain skeptical

March 18, 2019
By Brian Orelli
The use of contract research organizations (CROs) by drug developers has continued to grow at an 8 percent clip annually since 2010, reaching an estimated $86 billion in 2018, according to a new report from the Tufts Center for the Study of Drug Development (CSDD).
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Gtx-Oncternal hook up to form new public oncology company

March 8, 2019
By Brian Orelli
After Gtx Inc.'s only clinical candidate, selective androgen receptor modulator (SARM) enobosarm, failed to improve stress urinary incontinence in postmenopausal women, the company underwent a review of strategic alternatives. 
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Vertex batting 1,000 with 2 triples; bring in the 24-week closer data

March 7, 2019
By Brian Orelli
With positive phase III data in hand from its next-generation corrector, VX-659, Vertex Pharmaceuticals Inc. was in a no-lose situation as it released data from the cystic fibrosis (CF) phase III studies for its other next-generation corrector, VX-445.
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Pharma, VCs advise startups on best path for success

March 5, 2019
By Brian Orelli
SAN DIEGO – Advice for startups from pharma executives and venture capitalists abounded at the Biocom Global Life Science Partnering Conference last week.
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Pharma, VCs advise startups on best path for success

March 4, 2019
By Brian Orelli
SAN DIEGO – Advice for startups from pharma executives and venture capitalists abounded at the Biocom Global Life Science Partnering Conference last week.
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Agenus launches BEST: A crypto token for drugs

Feb. 25, 2019
By Brian Orelli
Blockchain has already infiltrated the drug industry, from tracking supply chain to information management system to cryptocurrencies to pay people for their genomic sequencing.
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Agenus launches BEST: A crypto token for drugs

Feb. 25, 2019
By Brian Orelli
Blockchain has already infiltrated the drug industry, from tracking supply chain to information management system to cryptocurrencies to pay people for their genomic sequencing. But now Agenus Inc. is looking to use the tracking technology to help fund drug development. The company announced plans to launch a Biotech Electronic Security Token (BEST), which will be tied to its anti-PD-1 antibody, AGEN-2034.
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Hibercell lands $61M series A to target dormant tumor cells

Feb. 11, 2019
By Brian Orelli
Backed by a $60.75 million series A round, Hibercell Inc. has launched with plans to tackle dormant disseminated tumor cells (DTCs).
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Orphan Technologies tackles rare, genetic homocystinuria

Feb. 7, 2019
By Brian Orelli
Spun out of work from Jan Kraus' lab at the University of Colorado in 2013, Orphan Technologies Ltd. has moved its first drug into the clinic. The Lexington, Mass.-based company is part of the Neopharm group, of Petach Tikva, Israel, a private company owned by a single family.
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Novartis says no thanks to Surface Oncology, again

Feb. 6, 2019
By Brian Orelli
Three-quarters of the way through a 2016 deal with Surface Oncology Inc., Novartis AG has only taken one drug from the collaboration under its wing.
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