In late May, Novartis AG's Avexis Inc. unit gained FDA approval for Zolgensma (onasemnogene neparvovec) to treat spinal muscular atrophy, and other companies are looking to follow suit developing drugs to treat a variety of diseases of the central nervous system (CNS).
In late May, Novartis AG's Avexis Inc. unit gained FDA approval for Zolgensma (onasemnogene neparvovec) to treat spinal muscular atrophy, and other companies are looking to follow suit developing drugs to treat a variety of diseases of the central nervous system (CNS).
Adding on to its $14 million series A round in April 2018, TFF Pharmaceuticals Inc. has secured another $8.17 million for the round to support development of its namesake thin film freezing (TFF) technology that was developed to increase the solubility of drugs.
Despite the strong growth in the number of drugs approved by the FDA over the last few years, clinical trial productivity fell 27% from 2013 to 2018, according to a report from the Iqvia Institute for Human Data Science.
Despite the strong growth in the number of drugs approved by the FDA over the last few years, clinical trial productivity fell 27% from 2013 to 2018, according to a report from the Iqvia Institute for Human Data Science.
Rather than develop vonoprazan in the U.S., Europe and Canada on its own, Takeda Pharmaceutical Co. Ltd. decided to spin the drug out into a new company, Phathom Pharmaceuticals Inc., with the help of venture capitalists at Frazier Healthcare Partners.
Looking to expand its glycogen synthase kinase-3 beta (GSK-3beta) inhibitor program, Northwestern University spinout Actuate Therapeutics Inc. has secured $21.7 million in a series B round led by Kairos Ventures. Defta Partners and Tech Coast Angels, with existing investor Bios Partners also participated in the round.
Rather than develop vonoprazan in the U.S., Europe and Canada on its own, Takeda Pharmaceutical Co. Ltd. decided to spin the drug out into a new company, Phathom Pharmaceuticals Inc., with the help of venture capitalists at Frazier Healthcare Partners.
About one in four drugs made it from being a new molecular entity (NME) in 2013 to approval in five years, according to a report on the pipeline progress for eight large biotechs analyzed by SVB Leerink analyst Geoffrey Porges. Externally acquired NMEs had a higher conversion rate, with 32% making it to market, compared to 21% of internally developed drugs.
