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BioWorld - Thursday, January 8, 2026
Home » Authors » Brian Orelli

Brian Orelli

Articles

ARTICLES

Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Cancer

Neok Bio launches with $75M to develop bispecific ADCs

Nov. 6, 2025
By Brian Orelli
No Comments
Neok Bio Inc. was formed earlier this year and is already on schedule to file an IND in a few months for its two bispecific antibody-drug conjugates (ADCs) to treat various types of tumors. The biotech got a leg up on development from its principal investor, Korean biotech ABL Bio Inc., where the discovery work was accomplished.
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Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Newco news

Neok Bio launches with $75M to develop bispecific ADCs

Nov. 5, 2025
By Brian Orelli
No Comments
Neok Bio Inc. was formed earlier this year and is already on schedule to file an IND in a few months for its two bispecific antibody-drug conjugates (ADCs) to treat various types of tumors.
Read More
Thymus illustration
Immune

Zag Bio launches with $80M to dampen immune response via thymus

Oct. 29, 2025
By Brian Orelli
No Comments
Zag Bio Inc. came out of stealth mode with $80 million in funding so far, including a recently closed series A financing, to develop its platform for autoimmune diseases using drugs targeted to the thymus where thymic regulatory cells are produced.
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Thymus illustration
Newco news

Zag Bio launches with $80M to dampen immune response via thymus

Oct. 28, 2025
By Brian Orelli
No Comments
Zag Bio Inc. came out of stealth mode with $80 million in funding so far, including a recently closed series A financing, to develop its platform for autoimmune diseases using drugs targeted to the thymus where thymic regulatory cells are produced.
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Drug R&D concept image.
Drug design, drug delivery & technologies

Flagship Pioneering launches Expedition to advance covalent-binding drugs

Oct. 23, 2025
By Brian Orelli
No Comments
Expedition Medicines, which Flagship Pioneering Inc. has incubated for the past three years, came out of stealth mode with a $50 million commitment from Flagship to support Expedition’s platform technology to discover small molecules that covalently bind to their target.
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Drug R&D concept image.
Newco news

Flagship Pioneering launches Expedition to advance covalent-binding drugs

Oct. 22, 2025
By Brian Orelli
No Comments
Expedition Medicines, which Flagship Pioneering Inc. has incubated for the past three years, came out of stealth mode with a $50 million commitment from Flagship to support Expedition’s platform technology to discover small molecules that covalently bind to their target.
Read More
Mast cell releasing histamine during allergic response
Immune

Excellergy launches with $70M for a new class of allergy drugs

Oct. 16, 2025
By Brian Orelli
No Comments
With $70 million in hand, Excellergy Inc. is ready to advance its lead candidate for allergic diseases into clinical trials. The series A round was led by Samsara Biocapital with co-investments from Red Tree Venture Capital and Decheng Capital.
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Mast cell releasing histamine during allergic response

Excellergy launches with $70M for a new class of allergy drugs

Oct. 13, 2025
By Brian Orelli
No Comments
With $70 million in hand, Excellergy Inc. is ready to advance its lead candidate for allergic diseases into clinical trials. The series A round was led by Samsara Biocapital with co-investments from Red Tree Venture Capital and Decheng Capital.
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Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Immune

Dualitas launches with $65M to advance bispecifics for I&I

Sep. 17, 2025
By Brian Orelli
No Comments
Dualitas Therapeutics Inc. exited stealth mode with a $65 million series A investment that was co-led by Versant Ventures and Qiming Venture Partners USA.
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Hand holding money plant
Newco news

Allrock snags $50M for its in-licensed ROCK inhibitor

Sep. 16, 2025
By Brian Orelli
No Comments
Allrock Bio Inc. secured $50 million in a series A round co-led by Versant Ventures and Westlake Biopartners to advance ROC-101, an oral pan-rho-associated protein kinase (ROCK) inhibitor to treat pulmonary arterial hypertension and pulmonary hypertension with interstitial lung disease.
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View All Articles by Brian Orelli

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