BioWorld. Link to homepage.

Clarivate
  • BioWorld
  • BioWorld Science
  • BioWorld Asia
  • Data Snapshots
    • Biopharma
    • Medical technology
    • Infographics: Dynamic digital data analysis
    • Index insights
    • NME Digest
  • Special reports
    • Infographics: Dynamic digital data analysis
    • Trump administration impacts
    • Med-tech outlook 2026
    • Under threat: mRNA vaccine research
    • BioWorld at 35
    • Biopharma M&A scorecard
    • Bioworld 2025 review
    • BioWorld MedTech 2025 review
    • BioWorld Science 2025 review
    • Women's health
    • China's GLP-1 landscape
    • PFA re-energizes afib market
    • China CAR T
    • Alzheimer's disease
    • Coronavirus
    • More reports can be found here

BioWorld. Link to homepage.

  • Sign In
  • Sign Out
  • My Account
Subscribe
BioWorld - Friday, April 10, 2026
Home » Authors » Brian Orelli

Brian Orelli

Articles

ARTICLES

Firms look to new MOAs to treat Alzheimer’s disease

March 7, 2016
By Brian Orelli
As Biogen Inc., Merck & Co. Inc. and Eli Lilly and Co. race to the finish line with their Alzheimer’s disease drugs that are in phase III development, two companies – Neuro-Bio Ltd. and Ironwood Pharmaceuticals Inc. – are just lacing up their shoes.
Read More

Panel: Cranking out biopharma newcos with a build-to-sell model

Feb. 29, 2016
By Brian Orelli
SAN DIEGO – At the Biocom Global Life Science Partnering Conference, biotech executives and venture capitalists shared their experiences building companies with the intention of selling to a big pharma.
Read More

Investors upbeat on biopharma but warn 2016 may be rough

Feb. 29, 2016
By Brian Orelli
SAN DIEGO – The mood at the Biocom Global Life Science Partnering Conference last week was generally upbeat on the long-term future of the sector, but venture capitalists, investment bankers, serial entrepreneurs, and other speakers at the conference warned that 2016 might be rough for raising capital.
Read More

Precision medicine pushes bioinformatics to the cloud

Feb. 22, 2016
By Brian Orelli
Like seemingly everything having to do with computers these days, bioinformatics is pushing into the cloud, allowing for cheaper and more efficient computation to identify potential targets for precision medicine.
Read More

Fighting resistance with novel mechanisms of action

Feb. 8, 2016
By Brian Orelli
With the rising increase in bacteria and fungus resistant to current medications, companies are developing drugs that use novel mechanisms of action to fight the bugs.
Read More

Pricing and integration keys for biotech moving forward

Feb. 1, 2016
By Brian Orelli
While the biotech industry has come a long way in developing new innovative drugs, companies will face external and internal issues in 2016, according to a new report from the Tufts Center for the Study of Drug Development (CSDD).
Read More

Injecting patient compliance into HIV drug regimens

Jan. 25, 2016
By Brian Orelli
Highly active antiretroviral therapies (HAART), combining multiple drugs into a cocktail, can effectively suppress HIV. But patient compliance in taking pills, especially after the virus becomes resistant and requires multiple pills per day, can be a challenge.
Read More

Big VC financing rounds lead to monster 4Q

Jan. 5, 2016
By Brian Orelli
Venture capitalists hit the ground running after returning from their summer vacations that saw third-quarter investments fall substantially from the first half. (See BioWorld Today, Oct. 2, 2015.)
Read More

If you can't beat 'em join 'em; looking for immuno-onc boost

Dec. 14, 2015
By Brian Orelli
Last week, Threshold Pharmaceuticals Inc. announced the failure of two phase III evofosfamide trials, one in pancreatic cancer and another in soft tissue sarcoma, but Barry Selick, CEO of the South San Francisco-based company, gave investors some hope that the drug might work in combination with immune checkpoint inhibitors.
Read More

If you can't beat 'em, join 'em; looking for immuno-onc boost

Dec. 12, 2015
By Brian Orelli

Last week, Threshold Pharmaceuticals Inc. announced the failure of two phase III evofosfamide trials, one in pancreatic cancer and another in soft tissue sarcoma, but Barry Selick, CEO of the South San Francisco-based company, gave investors some hope that the drug might work in combination with immune checkpoint inhibitors. (See BioWorld Today, Dec. 8, 2015.)


Read More
View All Articles by Brian Orelli

Popular Stories

  • Today's news in brief

    BioWorld
    BioWorld briefs for April 10, 2026.
  • Hengrui discovers new Nav1.8 blockers

    BioWorld Science
    Researchers from Jiangsu Hengrui Pharmaceuticals Co. Ltd. and Shanghai Hengrui Pharmaceutical Co. Ltd. have patented new sodium channel protein type 10 subunit α...
  • Cancer and blood cells

    Hematopoietic stem cell research points to leukemia’s early roots

    BioWorld Science
    Hematopoietic stem cell (HSC) research over the past century has shown that leukemia may be driven by an invisible hand of inflammation. The bone marrow and...
  • News in brief

    BioWorld Asia
    BioWorld Asia briefs for April 7, 2026
  • Connecting puzzle pieces

    Korsana boosts Alzheimer’s work with reverse merger, $380M financing

    BioWorld Science
    Just over a month after emerging from stealth and disclosing a $150 million series A, Korsana Biosciences Inc. is making the leap to the public market via a...
  • BioWorld
    • Today's news
    • Analysis and data insight
    • Clinical
    • Data Snapshots
    • Deals and M&A
    • Financings
    • Medical technology
    • Newco news
    • Opinion
    • Regulatory
  • BioWorld Science
    • Today's news
    • Biomarkers
    • Cancer
    • Conferences
    • Endocrine/metabolic
    • Immune
    • Infection
    • Neurology/psychiatric
    • NME Digest
    • Patents
  • BioWorld Asia
    • Today's news
    • Analysis and data insight
    • Australia
    • China
    • Clinical
    • Deals and M&A
    • Financings
    • Newco news
    • Regulatory
    • Science
  • More
    • About
    • Advertise with BioWorld
    • Archives
    • Article reprints and permissions
    • Contact us
    • Cookie policy
    • Copyright notice
    • Data methodology
    • Infographics: Dynamic digital data analysis
    • Index insights
    • Podcasts
    • Privacy policy
    • Share your news with BioWorld
    • Staff
    • Terms of use
    • Topic alerts
Follow Us

Copyright ©2026. All Rights Reserved. Design, CMS, Hosting & Web Development :: ePublishing