HONG KONG — A new Japanese and U.S. collaborative study showing that inhibition of the oxygen sensor prolyl hydroxylase domain-containing protein 2 (PHD2) in the liver enhanced uptake of lactate for glucose production and ameliorated lactic acidosis, suggests that PHD2 may be a viable new therapeutic target for patients with life-threatening lactic acidosis.
HONG KONG — A new Japanese and U.S. collaborative study showing that inhibition of the oxygen sensor prolyl hydroxylase domain-containing protein 2 (PHD2) in the liver enhanced uptake of lactate for glucose production and ameliorated lactic acidosis, suggests that PHD2 may be a viable new therapeutic target for patients with life-threatening lactic acidosis.
HONG KONG — A Japanese study has demonstrated how a phospholipid released by the nervous system’s glial cells controls the positioning of sensory neurons within the spinal cord, giving rise to the possibility that a lipid-based signaling system could be a therapeutic target for spinal cord injuries.
HONG KONG — A Japanese study has demonstrated how a phospholipid released by the nervous system's glial cells controls the positioning of sensory neurons within the spinal cord, giving rise to the possibility that a lipid-based signaling system could be a therapeutic target for spinal cord injuries.
HONG KONG — The findings of a new study of gene regulation by androgen receptor (AR) splice variants (AR-Vs) by U.S and Chinese scientists could provide a pivotal pathway for drug designers to target, in order to disrupt AR-V signaling as a novel strategy for the effective treatment of advanced prostate cancer.
HONG KONG — The findings of a new study of gene regulation by androgen receptor (AR) splice variants (AR-Vs) by U.S and Chinese scientists could provide a pivotal pathway for drug designers to target, in order to disrupt AR-V signaling as a novel strategy for the effective treatment of advanced prostate cancer.
HONG KONG — The discovery that a novel mechanism of CD4+ T helper (Th) cell differentiation is mediated by co-stimulation of glucocorticoid-induced tumor necrosis factor receptor- (TNFR)-related protein (GITR) explains the mechanism of action of GITR-mediated cancer immunotherapies and warrants clinical trials of GITR agonists, a Korean study has found.
HONG KONG — The discovery that a novel mechanism of CD4+ T helper (Th) cell differentiation is mediated by co-stimulation of glucocorticoid-induced tumor necrosis factor receptor- (TNFR)-related protein (GITR) explains the mechanism of action of GITR-mediated cancer immunotherapies and warrants clinical trials of GITR agonists, a Korean study has found.
HONG KONG – Two stem cell labs in China have independently reported the successful transformation of fibroblasts into functional neurons using only chemicals, with one group using human cells from healthy individuals and Alzheimer's patients, while the other used mouse cells, potentially providing other sources of neuronal cells for drug discovery and regenerative medicine.
HONG KONG – Two stem cell labs in China have independently reported the successful transformation of fibroblasts into functional neurons using only chemicals, with one group using human cells from healthy individuals and Alzheimer's patients, while the other used mouse cells, potentially providing other sources of neuronal cells for drug discovery and regenerative medicine.
