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BioWorld - Wednesday, February 11, 2026
Home » Authors » Elise Mak

Articles by Elise Mak

Hua Medicine’s GKA hits success in phase III type 2 diabetes trial

June 19, 2020
By Elise Mak
BEIJING – Diabetes-focused Hua Medicine (Shanghai) Ltd. became the first drugmaker to reveal phase III data of a glucokinase activator (GKA) designed to treat type 2 diabetes. On June 18, it said its first-in-class GKA, dorzagliatin, showed sustained efficacy and safety for the 52-week treatment period with reductions in HbA1c levels in a completed phase III trial as a monotherapy.
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Man wearing mask, receiving coronavirus vaccine

CNBG reports 100% seroconversion rate for COVID-19 vaccine candidate

June 17, 2020
By Elise Mak
BEIJING – Chinese state-backed vaccine developer China National Biotec Group (CNBG), of Beijing, said on Tuesday night that its inactivated COVID-19 vaccine candidate produced a seroconversion rate of up to 100% in a phase I/II trial that enrolled 1,120 healthy subjects.
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Canbridge moves to expand rare disease pipeline with UMass collaboration

June 16, 2020
By Elise Mak
BEIJING – Rare disease specialist Canbridge Pharmaceuticals Inc., of Beijing, said it is collaborating with the Horae Gene Therapy Center at the University of Massachusetts (UMass) Medical School to conduct gene therapy research with a focus on neuromuscular conditions.
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Business, data, dollars illustration

China’s CAR T developer JW Therapeutics closes $100M series B to advance CD19-targeted candidate

June 16, 2020
By Elise Mak
BEIJING – CAR T therapy developer JW Therapeutics (Shanghai) Co. Ltd. raised another $100 million this week after securing $90 million in series A round in 2018. The funds will continue to go toward its lead program, JWCAR-029, a CAR T-cell product targeting CD19 that is now in a phase II study.
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Coronavac product packaging

Sinovac unveils positive results for COVID-19 vaccine candidate, aims to start phase III next month

June 16, 2020
By Elise Mak
BEIJING – Nasdaq-listed Chinese vaccine developer Sinovac Biotech Ltd., of Beijing, said the preliminary results of the phase I/II trials of its COVID-19 inactivated vaccine candidate, Coronavac, demonstrated favorable immunogenicity and safety profiles.
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Yisheng vaccine candidate YS-SC2-010

Yisheng unveils PIKA adjuvanted recombinant protein vaccine candidate for COVID-19

June 16, 2020
By Elise Mak
BEIJING – One more company is joining the global efforts in developing a vaccine for COVID-19. Beijing-based Yisheng Biopharma Co. Ltd. unveiled YS-SC2-010, which was developed through recombinant protein technology and its proprietary PIKA (polyinosinic-polycytidylic acid-based adjuvant) technology.
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Coronavac product packaging

Sinovac unveils positive results for COVID-19 vaccine candidate, aims to start phase III next month

June 15, 2020
By Elise Mak
BEIJING – Nasdaq-listed Chinese vaccine developer Sinovac Biotech Ltd., of Beijing, said the preliminary results of the phase I/II trials of its COVID-19 inactivated vaccine candidate, Coronavac, demonstrated favorable immunogenicity and safety profiles.
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China’s CAR T developer JW Therapeutics closes $100M series B to advance CD19-targeted candidate

June 12, 2020
By Elise Mak
BEIJING – CAR T therapy developer JW Therapeutics (Shanghai) Co. Ltd. raised another $100 million this week after securing $90 million in series A round in 2018. The funds will continue to go toward its lead program, JWCAR-029, a CAR T-cell product targeting CD19 that is now in a phase II study.
Read More

Canbridge moves to expand rare disease pipeline with UMass collaboration

June 10, 2020
By Elise Mak
BEIJING – Rare disease specialist Canbridge Pharmaceuticals Inc., of Beijing, said it is collaborating with the Horae Gene Therapy Center at the University of Massachusetts (UMass) Medical School to conduct gene therapy research with a focus on neuromuscular conditions. The move is expected to add new assets to the company’s portfolio.
Read More
Chalkboard illustration: question mark, gears, lightbulb, target, rocket
Newco News

Shanghai startup Eccogene bets on small molecules for NASH

June 9, 2020
By Elise Mak
BEIJING – After his role as associate director and head of chemistry at Eli Lilly and Co., Brandeis-trained Jingye Zhou founded Eccogene Inc. in Shanghai in 2018 to focus on developing small-molecule drugs for metabolism and immune-related diseases.
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