Boston Scientific Corp. will acquire Symetis SA for $435 million in cash in an effort to broaden its transcatheter aortic valve replacement (TAVR) portfolio. The Ecublens, Switzerland-based company had been expected to list publicly at the end of this month on the Euronext Paris market in an offering slated to raise €55.8 million (US$59.9 million).

New research published in the BMJ finds that total knee replacement may be most useful in osteoarthritis patients with the most severe symptoms, with little quality of life or economic benefit from the use of the procedure in the less severe patient population. The researchers suggested that a more rigorous assessment for individual patients of the potential risks and benefits of knee replacement, as well as better optimization of more conservative interventions, could help to improve population-level outcomes and the economic utility of the procedure. The study authors call for further research to advance these...

New research published in the BMJ finds that total knee replacement may be most useful in osteoarthritis patients with the most severe symptoms, with little quality of life or economic benefit from the use of the procedure in the less severe patient population.

iCAD Inc. has secured a PMA approval from the FDA for the computer-aided detection product for digital breast 3-D tomosynthesis that is based on deep learning. The product is already available via Chicago-based partner GE Healthcare; the Nashua, N.H., start up is working now to make it available to other major tomosynthesis providers. Known as Powerlook Tomo Detection, it received a CE mark and Health Canada approval last year. In Europe, it's already in use at multiple high-volume breast imaging centers. APPLYING DEEP LEARNING "The way the product works is that we have developed a...

iCAD Inc. has secured a PMA approval from the FDA for the computer-aided detection product for digital breast 3-D tomosynthesis that is based on deep learning. The product is already available via Chicago-based partner GE Healthcare; the Nashua, N.H., start up is working now to make it available to other major tomosynthesis providers.

Corporate restart Renalguard Solutions Inc. has raised a $14.5 million series A round to get its device through an ongoing U.S. pivotal trial to protect against contrast-induced acute kidney injury and onto the market. Renalguard is designed to measure patient urine output in real-time and then to match that amount to hydration introduced during catheterization procedures. The Milford, Mass.-based company aims to have pivotal data in early 2018, which could be followed later next year by a PMA approval from the FDA. The financing will also go to support development of the device in additional...

Corporate restart Renalguard Solutions Inc. has raised a $14.5 million series A round to get its device through an ongoing U.S. pivotal trial to protect against contrast-induced acute kidney injury and onto the market. Renalguard is designed to measure patient urine output in real-time and then to match that amount to hydration introduced during catheterization procedures.