Synonymous or silent mutations do not change the sequence of the protein that they encode. With some exceptions, they do not trigger any effect. Last year, however, a study by researchers from the University of Michigan tried to refute this concept after finding that they altered the protein function. But breaking dogmas can have answers. A group of scientists from various institutions has found that this work could have a method error.

Research into how gross chromosomal rearrangements occur may have major implications for the discovery and development of new cancer therapies, according to a Japanese study reported in the July 22, 2021, edition of PLoS Genetics