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Home » Newsletters » BioWorld

BioWorld

Aug. 18, 2014

View Archived Issues

Achillion Pharmaceuticals sets stage for future Sovaldi battle with proxy study

Interim phase II data showing that an eight-week course of Achillion Pharmaceuticals Inc.'s NS5A inhibitor, ACH-3102, and Sovaldi (sofosbuvir, Gilead Sciences Inc.) in 12 hepatitis C virus (HCV) genotype 1 patients resulted in a complete sustained virologic response rate four weeks after treatment (SVR4) pushed company shares (Nasdaq:ACHN) up 9.6 percent to close at $9.25 Friday. Read More

Enter the Vertex vortex: IPO would 'Proqr' $75M for inhaled RNA bid in CF

Among the founders of cystic fibrosis (CF) player Proqr Therapeutics BV, which has filed to raise $75 million in an initial public offering (IPO), is a familiar name: Henri Termeer, former CEO of Genzyme Corp. Read More

High-flying Santhera gets $15M in share sale

DUBLIN – Santhera Pharmaceuticals AG, the hottest turnaround story in European biotech this year, raised CHF13.4 million (US$14.8 million) from a sale of treasury shares, as it prepares for a crunch meeting with the FDA to map out a regulatory approval pathway for its Duchenne muscular dystrophy (DMD) drug, idebenone (Catena/Raxone). Read More

Send in the 'caveolaery' and solve drug delivery problems

Finding a substance with activity against its intended target is only one of the challenges of any therapeutics development effort. Read More

Vyome adds $8M to advance pipeline against skin conditions

NEW DELHI – Indian biopharma company Vyome Biosciences raised almost $8 million in a second round of fundraising as part of a push to develop treatments for hard-to-treat skin conditions such as acne, persistent dandruff and bacterial and fungal skin infections. Read More

CBPO, Wuxi see growth, Sinovac sales drop, Sciclone holds steady

HONG KONG – Several major players in China's biopharmaceutical industry have released their second quarter and first-half 2014 financial results, with some companies having a better year than others so far. Read More

BioWorld explores Ebola drugs and vaccines in depth

Like other rare diseases, the development of vaccines and drugs to combat Ebola has been stymied by a lack of financial backing to move therapeutics through clinical trials. Read More

Other news to note

China YCT International Group Inc., of Shandong, China, said it signed a strategic cooperation agreement with Xi'an Putian Pharmacy LLP that will allow it to sell Huoliyuan capsules in 15 Chinese provinces. Terms were not disclosed. Read More

In the clinic

Neurovive Pharmaceutical AB, of Stockholm, said enrollment in its ongoing phase IIa study with Neurostat for treating patients with severe traumatic brain injury (TBI) is continuing, and another two patients have been enrolled, bringing the number to seven out of a total 20 patients that are targeted. Read More

Pharma: Other news to note

Mallinckrodt plc, of Dublin, said it completed its acquisition of Questcor Pharmaceuticals Inc., of Anaheim, Calif., in a cash and stock transaction valued at about $5.8 billion. Read More

Bench Press: BioWorld looks at translational medicine

Scientists from Washington University in St. Louis have discovered one mechanism by which Ebola virus shuts off the host immune response and, in particular, how the virus specifically prevents interferon from being transported to the cell's nucleus, where it sets off antiviral gene expression programs. Read More

Stock movers

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