BioSante Pharmaceuticals Inc., of Lincolnshire, Ill., reported disappointing results from its two pivotal Phase III trials of LibiGel (testosterone gel) for hypoactive sexual desire disorder in postmenopausal women. Read More
On Wednesday, Ariad Pharmaceuticals Inc. filed a shelf registration covering stock, debt securities, warrants and units. The company didn't leave investors in suspense for long. A day later, the company priced an underwritten public offering of 21.5 million shares of common stock at Wednesday's closing price of $10.42 per share, a discount of just 5.4 percent from Tuesday's closing price of $11.01. Read More
WASHINGTON – An FDA advisory committee faced some stark what-ifs this week in developing a treatment for a disease that no longer exists in the natural world. Read More
Back in September, Orexigen Therapeutics Inc.'s CEO told BioWorld Today that the firm hoped to avoid a near-term financing by securing an ex-U.S. partnership to help offset costs for the large cardiovascular outcomes trial (CVOT) required by the FDA to get obesity candidate Contrave (naltrexone HCl/buproprion) over the finish line. Read More
• Dicerna Pharmaceuticals Inc., of Watertown, Mass., said partner Kyowa Hakko Kirin Co. Ltd., of Tokyo, elected to advance the first collaborative oncology candidate from research stage into formal development studies, triggering a $5 million milestone payment. In addition, Kyowa exercised an option to bring a second cancer target into the collaboration. Read More
• Ampio Pharmaceuticals Inc., of Greenwood Village, Colo., received notices for allowance for two patents. The first is directed to a class of compounds combining elements of diketopiperazines and methylphenidate derives, while the second is directed to derivatives of methylphenidate (Ritalin). Read More
• Human Genome Sciences Inc., of Rockville, Md., and GlaxoSmithKline plc, of London, said they started dosing in BLISS-SC, a new Phase III trial of Benlysta (belimumab) administered subcutaneously once weekly to autoantibody-positive adults with active systemic lupus erythematosus (SLE). Read More
