Startup Delinia Inc. hitched its potentially transformative immune regulatory wagon to the Celgene Corp. train, agreeing to a potential $775 million acquisition the same day Celgene reported its fourth-quarter and full-year 2016 financial results. Read More
Despite a 22 percent decline in Biogen Inc.’s fourth-quarter income, attributable mostly to its recent settlement with Forward Pharma A/S, company shares (NASDAQ:BIIB) climbed 2 percent to $278.89 on Thursday after the company delivered 2017 guidance largely in line with analyst expectations and news that its launch of spinal muscular atrophy (SMA) drug Spinraza (nusinersen) was progressing, though more slowly than hoped amid insurer pushback. Read More
SHANGHAI – Beigene Co. Ltd., of Beijing, is advancing its small-molecule Bruton’s tyrosine kinase (BTK) inhibitor candidate, BGB-3111, in a global phase III trial for patients with Waldenström’s macroglobulinemia (WM, or lymphoplasmacytic lymphoma), a type of non-Hodgkin lymphoma. Read More
In 2012, BioWorld named the disconnect between science and clinical trials in Alzheimer’s disease (AD) as one of the top 10 stories of the year. (See BioWorld Today, Dec. 27, 2012.) Read More
An FDA request for more data doesn’t disqualify patent claims stemming from the research, the U.S. Court of Appeals for the Federal Circuit ruled Thursday in Cumberland Pharmaceuticals Inc. v. Mylan Inc. Read More
Verastem Inc., of Boston, said it dosed the first patient in a phase I/II trial testing avelumab (Merck KGaA and Pfizer Inc.), a fully human anti-PD-L1 IgG1 monoclonal antibody, in combination with Verastem’s defactinib, an FAK inhibitor, in patients with advanced ovarian cancer. Read More
Evotec AG, of Hamburg, Germany, said its wholly owned company, Cyprotex, has completed the relocation of its U.K. operations from Macclesfield to Alderley Park designed to consolidate operations into a single, state-of-the-art facility. The core capabilities include in vitro ADME services, mechanistic toxicology and high content toxicology screening services, and predictive modeling solutions. Read More
