Earlier this month, the U.S. Court of Appeals for the Federal Circuit upheld the validity of Myriad Genetics Inc.'s patent claims based on the composition of isolated DNA. (See BioWorld Today, Aug 17, 2012.) Read More
Finding next-generation treatments for pulmonary arterial hypertension (PAH) is proving to be difficult. Last week two companies made the point. Gilead Sciences Inc. terminated a Phase II trial of cicletanine for PAH due to a failure of the trial to meet its primary endpoint of improvement in exercise capacity; and Novartis AG pulled its new drug application (NDA) for QTI571 (imatinib mesylate) for PAH treatment.
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