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Home » Newsletters » BioWorld

BioWorld

Aug. 24, 2015

View Archived Issues

Parental advisory? Orphan firm Raptor draws doubt, praise for potential $418M Tripex deal

Pundits differed about Raptor Pharmaceutical Corp.'s buy of global rights to Quinsair for adult cystic fibrosis (CF) patients from Tripex Pharmaceuticals LLC for $68.4 million up front and as much as $350 million more in milestone payments. Read More

Organ-on-a-chip efforts seek to supplant preclinical animal models

Can government researchers, working in collaboration with industry and academia, build a better mousetrap for preclinical testing of therapeutic compounds that will be more predictive of their response in humans, without harming the mice? That question is at the heart of an initiative by the NIH's National Center for Advancing Translational Sciences (NCATS). Read More

Janus lands Roche deal, buyout option with preclinical TLR program

An exclusive new tie-up between Boston-based Janus Biotherapeutics Inc. and Roche AG will advance what could become the first oral Toll-like receptor (TLR) inhibitor to enter the clinic with the potential to address autoimmune diseases. Read More

No brainer: FTO's effects on weight are peripheral effect

In genomewide association studies (GWAS), a variant in the gene FTO is the strongest obesity-correlated signal in the human genome. Since it was first flagged by GWAS seven years ago, though, why FTO is so strongly linked to obesity has remained a puzzle. Read More

Korea's Bioepis eyeing rare Nasdaq listing as it advances biosimilars

HONG KONG – In a move that will give its parent group a debut listing in the U.S., South Korean biotech company Samsung Bioepis said it will aim for a Nasdaq listing. Read More

Financings

Nemus Bioscience Inc., a Costa Mesa, Calif.-based company focused on the discovery, development and commercialization of cannabis-based therapeutics through a partnership with the University of Mississippi, closed a series B convertible preferred stock financing for gross proceeds of $5 million. Read More

Other news to note

Cellectar Biosciences Inc., of Madison, Wis., introduced its phospholipid ether-drug conjugate (PDC) platform for expanding the use of its small-molecule cancer-targeting and delivery technology for chemotherapeutics. Read More

Stock movers

Read More

In the clinic

60 Degrees Pharmaceuticals LLC, of Washington, said Singapore General Hospital (SGH) received a grant from Singapore's National Medical Research Council to support a phase II trial among dengue fever patients. Read More

Bench Press: BioWorld looks at translational medicine

Researchers from Lawrence Berkeley National Laboratory have reported they were able to delay the onset of Huntington’s disease by preventing somatic expansion of the CAG triplet repeat that is found in mutant huntingtin and is the cause of Huntington’s disease. Read More

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