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Home » Newsletters » BioWorld

BioWorld

Aug. 12, 2011

View Archived Issues

Complera Nod Bridges Gilead's HIV Franchise; All Eyes on Quad

Gilead Sciences Inc.'s Complera (emtricitabine/rilpivirine/tenofovir disoproxil fumarate) won FDA approval as expected, but the single-tablet formulation nicknamed "Btripla" likely will prove only a modest addition to the firm's HIV franchise should the highly anticipated Quad regimen yield strong Phase III data later this year. Read More

Chimeric Immune Cells Lead To Advanced Leukemia Remissions

Dendreon's Corp's Provenge (sipuleucel-T), the first FDA-approved cancer immunotherapy, may have had an underwhelming welcome from the medical community. (See BioWorld Today, Aug. 5, 2011.) Read More

Jennerex's $8.6M Financing Boosts Cancer Pipeline

Jennerex Inc. completed a private placement of $8.6 million in gross proceeds to support development of its lead cancer candidate, JX-594. The product, an oncolytic virus, has shown antitumor activity in Phase I and Phase II trials, with demonstrated overall survival benefit in advanced liver cancer. Read More

OncoSec Medical Advances Electroporation Technology

OncoSec Medical Inc. is a lot younger than it looks, with a pipeline that would make much older start-ups envious. Read More

Extra! Extra! Leukemia Therapy Purposely Misses Holy Grail!

This week's report of remissions in three advanced leukemia patients after immunotherapy has generated quite a lot of excitement in the media – which, in turn, has led to some backlash amongst the twitterati and in the blogosphere, noting that two complete remissions plus a partial one don't make a blockbuster. Or anything, really, that will be broadly useful within the next few years. Read More

Stock Movers

Read More

Coming Monday in BioWorld Insight

The last four years have brought significant CEO turnover, not just in big pharma, but in biotech as well. Read More

Clinic Roundup

• Lexicon Pharmaceuticals Inc., of The Woodlands, Texas, published Phase II data showing LX1031 was well tolerated and provided relief from pain and discomfort in non-constipating irritable bowel syndrome. The data were published in Gastroenterology. LX1031 is a tryptophan hydroxylase inhibitor. Read More

Other News To Note

• Neoprobe Corp., of Dublin, Ohio, submitted a new drug application to the FDA for Lymphoseek (tilmanocept) for use in intraoperative lymphatic mapping. The procedure, which identifies and biopsies lymph nodes draining the area around a tumor, is used primarily in melanoma and breast cancer. Read More

Appointments and Advancements

• Stem Cell Therapeutics Corp., of Calgary, Alberta, appointed David Allan executive chairman. Read More

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