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Home » Newsletters » BioWorld

BioWorld

Feb. 6, 2012

View Archived Issues

Merck, Threshold Shake Hands in $550M Cancer Collaboration

Stock in Threshold Pharmaceuticals Inc. surged more than 131 percent on news that it signed a deal with Merck KGaA valued at up to $550 million to develop and commercialize Threshold's cancer candidate, TH-302. Read More

Antibiotic Firm Cempra Hangs in After Price Cut on $50M IPO

If you were looking for a sign that post-J.P. Morgan optimism and a flurry of drug approvals might blow the biotech initial public offering (IPO) window open again – keep looking. Read More

Resveratrol's Effects On Sirtuins May Be Mimicked by COPD Drug

Resveratrol, a compound found in minuscule doses in foods including red wine and chocolate, is as close to ambrosia – the food of the ancient Greek Gods that gave them eternal youth – as anyone has come. It activates sirtuins and mimics the effects of caloric restriction, which is the only known way to reliably increase lifespan. Read More

Biopharma Speeding Down New Biosimilar Pathway

WASHINGTON – Companies chasing down biosimilars are not letting the lack of guidance slow them down. Read More

Gilead's HCV Data Eclipse Fourth-Quarter Earnings Miss

Gilead Sciences Inc.'s fourth-quarter earnings fell short of expectations, but the Foster City, Calif.-based firm's stock jumped Friday on promising early data from newly acquired hepatitis C virus (HCV) drug GS-7977. Read More

Other News To Note

• Retrosense Therapeutics LLC, of Ann Arbor, Mich., received a grant of $250,000 from the Foundation Fighting Blindness to support development of its investigational gene therapy product based on genes from blue-green algae. The foundation may invest additional funds upon achievement of certain milestones in the research. The company anticipates beginning clinical trials in two to four years. Read More

Clinic Roundup

• Exelixis Inc., of South San Francisco, reported preliminary data from a Phase Ib drug interaction trial of cabozantinib in renal cell carcinoma, showing a high rate of durable tumor response, with a low rate of primary refractoriness to drug therapy, and a long median progression-free survival. Read More

Bench Press

Researchers from the Japanese Osaka University have uncovered an unexpected mechanism by which autoimmune T cells cross the blood-brain barrier in mice with the animal equivalent of multiple sclerosis. Read More

Stock Movers

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