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BioWorld - Thursday, December 11, 2025
Home » Newsletters » BioWorld

BioWorld

Nov. 3, 2016

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In the clinic

Trillium Therapeutics Inc., of Toronto, said it advanced TTI-621, an SIRPa-IgG1 Fc fusion protein, from dose escalation into phase Ib cohort expansion enrollment in patients with advanced hematologic malignancies. Read More

Other news to note

Celldex Therapeutics Inc., of Hampton, N.J., said it has inked an agreement to acquire privately held Kolltan Pharmaceuticals Inc., of New Haven, Conn. Read More

Earnings

Alkermes plc, of Dublin, reported that its total revenues for the third quarter of 2016 were $180.2 million compared to $152.7 million for the same period in 2015. Read More

Appointments and advancements

Siga Technologies Inc., of New York, named Phil Gomez CEO, and appointed Eric Rose executive chairman of the board. Read More

Financings

Cidara Therapeutics Inc., of San Diego, has entered an agreement with Square 1 Bank, a division of Pacific Western Bank, for a $20 million credit facility. Read More

Female sexual disorder reload in Palatin's phase III victory

The world had to wait for them about a month longer than expected, but Palatin Technologies Inc.'s positive phase III data with bremelanotide in premenopausal women diagnosed with hypoactive sexual desire disorder (HSDD) should turn up the heat on already busy partnering talks. Read More

Leo Pharma taps Morphosys to fuel dermatology ambitions

Leo Pharma A/S is again raising its bet on the promise of biologics to address important skin diseases, dealing in Morphosys AG and its Ylanthia antibody platform for a multi-target deal. The collaboration could yield multiple new dermatology therapies and milestone payments for Morphosys of up to €111.5 million (US$123.9 million) per program. Read More

Life sciences scrambles in anticipation of post-Brexit scenarios

LONDON – Four months from the referendum vote to leave the EU and – with the exception of a "commercially confidential" sweetheart deal with the Japanese car manufacturer Nissan – no company or sector is any clearer about the terms on which the U.K. government will seek to negotiate Brexit. Read More

Avexis shakes up SMA space with pivotal trial plan

Avexis Inc. is preparing for a David-and-Goliath showdown with Biogen Inc. and its partner, Ionis Pharmaceuticals Inc., after the FDA green-lighted the design of a pivotal trial for the upstart's gene therapy candidate, AVXS-101, in infants and children with spinal muscular atrophy (SMA) type 1. Read More

Cempra in free fall before adcom for its lead antibiotic

What a difference a few days and an FDA review can make. A week ago, Cempra Inc. (NASDAQ:CEMP) was trading just shy of $24. Wednesday, it closed at $7.30, down 60.9 percent in the company's heaviest day of trading ever. Read More

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