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Home » Newsletters » BioWorld

BioWorld

Sep. 2, 2015

View Archived Issues

Valeant fills Amgen gap as Astrazeneca hands off brodalumab; $100M up front

Valeant Pharmaceuticals International Inc. picked up the brodalumab torch dropped in May by Amgen Inc., inking an exclusive license with Astrazeneca plc to develop and commercialize the interleukin (IL)-17 inhibitor in moderate to severe plaque psoriasis and psoriatic arthritis (PsA). Read More

'Patients' pays off for Trevena pain phase IIb as TRV130 score keen over morphine – again

Self-administered pain therapy by way of a patient-controlled analgesia (PCA) device in Trevena Inc.'s phase IIb trial let TRV130's attention-getting safety profile emerge, and Wall Street didn't miss the significance, pushing the shares (NASDAQ:TRVN) by the end of the day to $9.05, up $3.05, or 50.8 percent. Read More

Heat seeks spark in checkpoint inhibitors

Heat Biologics Inc. is winding down a phase II study of its injectable adenocarcinoma cell vaccine, HS-110 (viagenpumatucel-L), in combination with low-dose cyclophosphamide, to focus instead on the potential benefits of combining the vaccine with Opdivo (nivolumab, Bristol-Myers Squibb Co.) to battle non-small-cell lung cancer (NSCLC). Read More

Exscientia delivers first compound in Sumitomo deal within 12 months

LONDON – Exscientia Ltd. said it has demonstrated its automated medicinal chemistry technology can cut the time and cost taken to design and optimize a drug by 75 percent, while improving the quality of the resulting molecule. Read More

Stem cell regulations easing China's move toward cell therapy

HONG KONG – Although authorities only allow studies linked to stem cells at the moment, the launch of China's first official regulations on stem cell studies may prove to be good news to the country's cell therapy industry. Read More

Regulatory front

Amarin Corp. plc and the FDA are trying to settle their differences over what truthful statements the Dublin-based drugmaker may make about off-label uses of its fish oil drug Vascepa. Read More

Stock movers

Read More

Financings

Sancilio Pharmaceuticals Inc., of Riviera Beach, Fla., has filed its S-1 to raise up to $86.25 million in an IPO. Read More

In the clinic

Allergy Therapeutics plc, of Worthing, UK, said the first patient was enrolled in its Pollinex Quattro birch dose-ranging study conducted in Germany and Austria. Read More

Other news to note

Obseva SA, of Plan-les-Ouates, Switzerland, reported data from ex-vivo pharmacology studies of lead compound, OBE001, at the European Society for Translational Medicine meeting in Vienna. Read More

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