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Home » Newsletters » BioWorld

BioWorld

April 6, 2018

View Archived Issues

Conatus shares cave after top-line miss in phase IIb emricasan trial

Following Wednesday's market close, Steven Mento, president, CEO and co-founder of Conatus Pharmaceuticals Inc., carefully walked analysts and investors through the rationale, design and opportunities to learn from the phase IIb POLT-HCV-SVR trial of individuals with post-transplant fibrosis and cirrhosis – a group, he emphasized on the conference call, that's not been studied previously. Read More

Consider the Lillys: Other CETP bids wilt but Dalcor genotyped effort thriving

Last August, after Merck & Co. Inc. disclosed positive but not especially compelling results with its cholesteryl ester transfer protein (CETP) inhibitor, anacetrapib, Credit Suisse analyst Vamil Divan concluded that the company made the right decision to quit, although drugs in the class "may still have a role in patients with certain genetic predispositions." Read More

Abbvie protects its nest egg, gives some certainty to Humira biosimilar market

Even though Humira's U.S. composition of matter patent expired more than a year ago and biosimilars are waiting to roll out, a basket lined with other patents will continue to protect Abbvie Inc.'s nest egg in the U.S. for a few more years. Read More

Researchers disagree on whether adults make new brain cells

Healthy brains continue to generate new neurons into old age, though they show reduced neural plasticity and angiogenesis, researchers from Columbia University reported in the April 5, 2018, issue of Cell Stem Cell. Read More

Australia's Kazia brings Genentech brain cancer molecule to phase II

PERTH, Australia – Sydney-based Kazia Therapeutics Ltd. has begun a U.S. phase II trial in glioblastoma with lead candidate GDC-0084, in-licensed from Roche Holding AG unit Genentech. Read More

Financings

Quralis Corp., of Cambridge, Mass., received undisclosed seed funding from MP Healthcare Venture Management, Amgen Ventures and Alexandria Venture Investments. The company is developing precision therapies to treat amyotrophic lateral sclerosis. Read More

Regulatory front

Ohio Department of Insurance Director Jillian Froment issued a bulletin requiring heightened protections for Ohio consumers related to prescription drug prices.  Read More

Other news to note

Elsalys Biotech SAS, of Lyon, France, is analyzing data from 147 patients with steroid-resistant graft-vs.-host disease treated with Leukotac (inolimomab) in an early access program.  Read More

Clinical data for April 5, 2018

Read More

Regulatory actions for April 5, 2018

Read More

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