Did all the venture capitalists get washed out to sea by Superstorm Sandy? Maybe they all followed in Benedict's footsteps and resigned? Because they sure weren't doing very many deals in the first quarter. Read More
Clavis Pharma AS has been hit by the Phase III failure of elacytarabine, its lipid-enhanced version of cytarabine, in a 380-patient trial in advanced acute myeloid leukemia (AML). Read More
Chimerix Inc. and Omthera Pharmaceuticals Inc. – one with an antiviral based on lipid delivery, the other with a lipid-lowering therapy – established terms for their initial public offerings (IPOs), raising investor hopes for a debut like that experienced last month by Enanta Pharmaceuticals Inc., but whether the fabled "window" will open for biotech firms this year remains in question. Read More
Recognizing the global impact its decision could have, the Supreme Court of India denied an appeal by Novartis AG, ending the company's 15-year quest for a patent for its cancer drug Gleevec/Glivec. Read More
Just a year out of the gate and with less than $1 million in funding, Milo Biotechnology LLC already has an FDA-sanctioned investigational new drug (IND) application and is in human trials with follistatin, a protein that increases muscle strength and prevents atrophy. Read More
The FDA released a draft guidance to help biosimilar sponsors request and be better prepared for formal meetings with the agency about product development. Read More
• ArQule Inc., of Woburn, Mass., said it regained worldwide rights to compounds covered under its AKT collaboration with Daiichi Sankyo Co. Ltd., of Tokyo, including lead compound ARQ 092. Read More
• Tengion Inc., of Winston-Salem, N.C., said the firm's clinical trial application was accepted in Sweden to start a Phase I trial testing its Neo-Kidney Augment in up to five patients with advanced chronic kidney disease. Read More
• Ferro Corp., of Cleveland, sold its pharmaceuticals business, Pfanstiehl Laboratories, to PLI Holdings Inc., an affiliate of Med Opportunity Partners LLC, for $16.9 million in cash and an earn-out incentive payment of up to $8 million, payable over two years based on earnings targets. Read More
