Researchers have discovered that insulin-like growth factor 2 or IGF2, a protein so far best known for its growth-promoting actions during pregnancy, can strengthen memories and prevent forgetting. Read More
A lot of companies start with an idea, and build a business around it. Jupiter, Fla.-based GLG Pharma LLC started with a business, in search of an idea. Read More
ArQule Inc., of Woburn, Mass., completed its public offering of 7 million shares priced at $6.15 each and said underwriters exercised their full 1.05 million share overallotment option. Read More
Inovio Pharmaceuticals Inc., of Blue Bell, Pa., said preclinical data using its next-generation intradermal electroporation delivery devices showed DNA delivery yielded levels of immunogenicity in terms of both antibody and T-cell responses and/or efficacy against a virus challenge that is comparable to intramuscular electroporation devices currently in testing. Read More
Calling it a "temporary setback," "easily remedied" and "relatively immaterial," analysts played down the negative impact of the FDA's refuse-to-file (RTF) letter to Gilead Sciences Inc. for its new drug application (NDA) seeking approval of HIV single-tablet regimen Truvada (emtricitabine/tenofovir disoproxil fumarate) plus Tibotec Pharmaceuticals Ltd.'s TMC278 (rilpivirine). Read More
LONDON – Prosensa NV announced that the first patient has started treatment in the Phase III trial of its lead antisense product for treating the progressive, inherited muscle-wasting disease Duchenne's muscular dystrophy (DMD). Read More
Photocure ASA, of Oslo, Norway, reported Phase II results showing that Cevira, a photodynamic therapy that combines a drug formulation and a medical device designed for the nonsurgical treatment of cervical human papillomavirus infection and precancerous lesions of the cervix, produced a three-month response rate of 71 percent in patients with mild cervical abnormalities vs. 43 percent in the control group. Read More
